| Mae Martin: SAP | 2023 | Director | Director |
| Broad City | 2017–2019 | Director | Director |
| The Untitled Webseries That Morgan Evans Is Doing TV Series | 2012 | Director | Director |
| A League of Their Own | 2022 | Writer | created by |
| Broad City | 2014–2019 | Writer | created by |
| Hack Into Broad City | 2017 | Writer | Writer |
| The Characters | 2016 | Writer | consultant writer |
| Broad City | 2010–2011 | Writer | creator |
| No Good Deed | 2024 | Actress | Leslie Fisher |
| Interior Chinatown | 2024 | Actress | Kleen Stik Commercial (voice) |
| Hot White Heist 2 | 2024 | Actress | Sam |
| The Second Best Hospital in the Galaxy | 2024 | Actress | Dr. Zypha (voice) |
| Officer Stanley | 2024 | Actress | Paramedic W. Rist |
| Big Envelopes Podcast Series | 2023 | Actress | Kelly Pritzker |
| Disenchantment | 2018–2023 | Actress | Bean (voice) |
| A League of Their Own | 2022 | Actress | Carson Shaw |
| Dog Cop 7: The Final Chapter | 2021 | Actress | Dog Cop |
| Hot White Heist | 2021 | Actress | Sam (voice) |
| The Mitchells vs. the Machines | 2021 | Actress | Katie |
| Curb Your Enthusiasm | 2020 | Actress | Diane |
| Bob's Burgers | 2020 | Actress | Megan (voice) |
| Broad City | 2014–2019 | Actress | Abbi Abrams |
| Hack Into Broad City | 2014–2019 | Actress | Abbi Abrams |
| BoJack Horseman | 2016–2018 | Actress | Emily (voice) |
| 6 Balloons | 2018 | Actress | Katie |
| Drunk History | 2018 | Actress | Gloria Steinem |
| Pickle and Peanut | 2015–2018 | Actress | Sneaky Patty (voice) |
| The Lego Ninjago Movie | 2017 | Actress | Nya (voice) |
| Portlandia | 2017 | Actress | Burning Man Girl |
| Person to Person | 2017 | Actress | Claire |
| The Master | 2016 | Actress | Chicken (voice) |
| Neighbors 2: Sorority Rising | 2016 | Actress | Jessica Baiers |
| The Characters | 2016 | Actress | Abbi |
| The Untitled Web Series That Morgan Evans Is Doing for MTV | 2015 | Actress | Blanche |
| Brief But Spectacular TV Series | 2015 | Actress | |
| Inside Amy Schumer | 2015 | Actress | Abbi |
| Lucas Bros Moving Co | 2015 | Actress | Sister Sister (voice) |
| High and Dry | 2014 | Actress | Studio Mate |
| Intimate Semaphores | 2014 | Actress | Studio Mate (segment "High and Dry") |
| Dropout | 2013 | Actress | |
| The Lineup TV Series | 2013 | Actress | |
| Chronic Gamer Girl | 2012 | Actress | |
| Rejected Pitches TV Series | 2012 | Actress | Amy Heckerling |
| Moms v. Pros TV Mini Series | 2012 | Actress | |
| Jest Originals | 2012 | Actress | Reenactment Amanda |
| Upload Short | 2011 | Actress | Elaine |
| Special Things to Do | 2011 | Actress | Mary |
| Broad City | 2010–2011 | Actress | Abbi |
| Doritos Robbers Short | 2010 | Actress | |
| Vag Magazine | 2010 | Actress | Moon Cup |
| Acting Reel Master Database TV Series | 2010–2011 | Actress | Daughter of Smoker |
| Revelation 13 | 2009 | Actress | Danielle |
| Officer Stanley | 2024 | Producer | producer |
| Big Envelopes Podcast Series | 2023 | Producer | executive producer |
| A League of Their Own | 2022 | Producer | executive producer (showrunner) |
| Broad City | 2014–2019 | Producer | executive producer (showrunner) |
| Hack Into Broad City | 2015–2019 | Producer | executive producer |
| The Realest Real | 2016 | Thanks | special thanks |
| 49th Annie Awards TV Special | 2022 | Soundtrack | performer: "Live Your Life" (uncredited) |
| Late Night with Seth Meyers | 2016 | Soundtrack | performer: "Oklahoma" |
| The Tonight Show Starring Jimmy Fallon | 2016 | Soundtrack | performer: "I Don't Want to Wait" |
| The Drew Barrymore Show | 2021–2023 | Self | Self - Guest |
| Wait Wait... Don't Tell Me! | 2022 | Self | Self - Guest |
| Today | 2016–2022 | Self | Self - Guest |
| PBS News Weekend | 2022 | Self | Self |
| CBS Mornings | 2022 | Self | Self |
| The Daily Show: Ears Edition | 2022 | Self | Self |
| The Daily Show | 2015–2022 | Self | Self - Guest |
| Jimmy Kimmel Live! | 2015–2022 | Self | Self - Guest |
| Entertainment Tonight | 2021–2022 | Self | Self |
| The 2022 ESPY Awards | 2022 | Self | Self - Presenter |
| Girls on Film | 2022 | Self | Self (voice) |
| The Tonight Show Starring Jimmy Fallon | 2015–2021 | Self | Self - Guest |
| Conan O'Brien Needs a Friend | 2021 | Self | Self - Guest |
| Hollywood Insider | 2021 | Self | Self |
| The 72nd Primetime Emmy Awards | 2020 | Self | Self |
| Cheat Sheet for the Voting Booth TV Series | 2020 | Self | Self - Guest |
| To Tell the Truth | 2020 | Self | Self - Panelist |
| Life is Short with Justin Long | 2020 | Self | Self - Guest |
| Visible: Out on Television | 2020 | Self | Self (creator - Broad City) |
| Good Mythical Morning | 2019 | Self | Self |
| Abbi and Ilana's Broad City | 2019 | Self | Self |
| Hot Ones | 2019 | Self | Self - Guest |
| Live with Kelly and Mark | 2015–2019 | Self | Self - Guest |
| 21st Annual Mark Twain Prize for American Humor celebrating: Julia Louis-Dreyfus | 2018 | Self | Self |
| Good Morning America | 2016–2018 | Self | Self - Guest |
| The Girl in the Show | 2018 | Self | Self |
| The 70th Primetime Emmy Awards | 2018 | Self | Self - Presenter |
| RuPaul's Drag Race | 2018 | Self | Self - Guest Judge |
| The Chris Gethard Show | 2015–2018 | Self | Self - Guest |
| Watch What Happens Live with Andy Cohen | 2017 | Self | Self - Guest |
| Watch What Happens Live with Andy Cohen | 2016–2017 | Self | Self - Guest |
| Late Night with Seth Meyers Podcast | 2017 | Self | Self - Guest |
| Late Night with Seth Meyers | 2014–2017 | Self | Self - Guest |
| Night of Too Many Stars | 2017 | Self | Self |
| Conan | 2017 | Self | Self - Guest |
| Larry King Now | 2017 | Self | Self - Guest |
| Made in Hollywood | 2017 | Self | Self |
| Dish Nation | 2017 | Self | Self |
| Chelsea | 2017 | Self | Self - Guest |
| 2017 MTV Video Music Awards | 2017 | Self | Self - Opening Skit |
| Nylon News TV Series | 2017 | Self | Self |
| A Piece of Work Podcast Series | 2017 | Self | Self - Host |
| UCB Comedy Originals | 2017 | Self | Self |
| WGN Morning News | 2016 | Self | Self |
| The Late Show with Stephen Colbert | 2015–2016 | Self | Self - Guest |
| Emmy Quickie TV Series | 2016 | Self | Self |
| Last Week | 2016 | Self | Self |
| The Late Late Show with James Corden | 2016 | Self | Self - Guest |
| The View | 2016 | Self | Self - Guest |
| WTF with Marc Maron | 2016 | Self | Self - Guest |
| An Ode to Hannibal Buress | 2016 | Self | Self |
| Lip Sync Battle | 2015 | Self | Self - Competitor |
| The Meltdown with Jonah and Kumail | 2015 | Self | Self - Host |
| The Nightly Show with Larry Wilmore | 2015 | Self | Self - Panelist |
| Table for Two TV TV Mini Series | 2015 | Self | Self - Guest |
| Night of Too Many Stars: America Comes Together for Autism Programs | 2015 | Self | Self |
| Late Show with David Letterman | 2015 | Self | Self - Guest |
| Comedy Central's All-Star Non-Denominational Christmas Special | 2014 | Self | |
| Brunch Night with Jamie LeeLo TV Series | 2014 | Self | Self - Guest |
| The George Lucas Talk Show: Stage Show | 2014 | Self | Self |
| Getting Doug with High | 2014 | Self | Self |
| @midnight | 2014 | Self | Self |
| Chronic Gamer Girl | 2013 | Self | Self - Guest |
| Inside the Actor's Studio Apartment TV Series | 2011 | Self | Self - Guest |
| Entertainment Tonight | 2021–2022 | Archive Footage | Self (archive footage) |
| The Chris Gethard Show: The Cable Years - Web Videos TV Series | 2018 | Archive Footage | Self (archive footage) |
| Live with Kelly and Mark | 2016 | Archive Footage | Self (archive footage) |