| Gentefied | 2020–2021 | Director | Director |
| Superstore | 2017–2020 | Director | Director |
| Spidey and His Amazing Friends | 2025 | Actress | Woman |
| What If...? | 2024 | Actress | Ranger Morales (voice) |
| Quest for Craft TV Series | 2024 | Actress | |
| Dumb Money | 2023 | Actress | Jenny |
| Barbie | 2023 | Actress | Gloria |
| WeCrashed | 2022 | Actress | Elishia Kennedy |
| Superstore | 2015–2021 | Actress | Amy |
| Gentefied | 2020 | Actress | Andy Cruz |
| How to Train Your Dragon: Homecoming | 2019 | Actress | Astrid (voice) |
| DreamWorks Dragons: Dawn of New Riders | 2019 | Actress | Astrid (voice) |
| How to Train Your Dragon: The Hidden World | 2019 | Actress | Astrid (voice) |
| Dragons: Race to the Edge | 2015–2018 | Actress | Astrid (voice) |
| Gente-fied: The Digital Series | 2017 | Actress | |
| Jay-Z feat. Beyoncé: Family Feud | 2017 | Actress | America |
| Curb Your Enthusiasm | 2017 | Actress | Lin's Wife |
| Who Is? | 2017–2018 | Actress | (voice) |
| NBC Fall Primetime Preview TV Movie | 2016 | Actress | Amy |
| Special Correspondents | 2016 | Actress | Brigida |
| Inside Amy Schumer | 2015 | Actress | Mena |
| Last Week Tonight with John Oliver | 2015 | Actress | Maternity |
| What's Your Emergency | 2015 | Actress | Brenda Fitzgerald |
| Dragons: Dawn of the Dragon Racers | 2014 | Actress | Astrid (voice) |
| How to Train Your Dragon 2 | 2014 | Actress | Astrid (voice) |
| X/Y | 2014 | Actress | Silvia |
| DreamWorks Dragons | 2012–2014 | Actress | Astrid (voice) |
| Cesar Chavez | 2014 | Actress | Helen Chavez |
| The Good Wife | 2011–2013 | Actress | Natalie Flores |
| Sid the Science Kid: The Movie | 2013 | Actress | Dr. Cordova (voice) |
| Dreamworks How to Train Your Dragon Legends | 2010–2013 | Actress | Astrid (voice) |
| End of Watch | 2012 | Actress | Orozco |
| Christine | 2012 | Actress | Christine |
| It's a Disaster | 2012 | Actress | Hedy |
| Sid the Science Kid | 2011 | Actress | Dr. Cordova (voice) |
| Book of Dragons | 2011 | Actress | Astrid (voice) |
| Dragons: Gift of the Night Fury | 2011 | Actress | Astrid Hofferson (voice) |
| Funny or Die Presents... | 2011 | Actress | Emmy Presenter (segment "Paco Dances") |
| Legend of the Boneknapper Dragon | 2010 | Actress | Astrid (voice) |
| The Mis-Informant - with Jack Black as Nathan Spewman | 2010 | Actress | Teacher |
| Ugly Betty | 2006–2010 | Actress | Betty Suarez |
| How to Train Your Dragon | 2010 | Actress | Astrid (voice) |
| Our Family Wedding | 2010 | Actress | Lucia Ramirez |
| The Dry Land | 2010 | Actress | Sarah |
| Tinker Bell | 2008 | Actress | Fawn (voice) |
| The Sisterhood of the Traveling Pants 2 | 2008 | Actress | Carmen Lowell |
| Towards Darkness | 2007 | Actress | Luiza |
| Muertas | 2007 | Actress | Rebecca |
| Under the Same Moon | 2007 | Actress | Martha |
| Steel City | 2006 | Actress | Amy Barnes |
| 3:52 | 2005 | Actress | Kate |
| Lords of Dogtown | 2005 | Actress | Thunder Monkey |
| The Sisterhood of the Traveling Pants | 2005 | Actress | Carmen |
| How the Garcia Girls Spent Their Summer | 2005 | Actress | Blanca |
| $5.15/Hr. | 2004 | Actress | |
| CSI: Crime Scene Investigation | 2004 | Actress | April Perez |
| Plainsong | 2004 | Actress | Victoria Roubideaux |
| Darkness Minus Twelve | 2004 | Actress | Luiza |
| Touched by an Angel | 2002 | Actress | Charlee Wells |
| American Family | 2002 | Actress | |
| Gotta Kick It Up! | 2002 | Actress | Yolanda |
| Real Women Have Curves | 2002 | Actress | Ana Garcia |
| Gentefied | 2020–2021 | Producer | executive producer |
| Superstore | 2015–2021 | Producer | executive producer |
| Superstore: An Evening in Cloud 9 | 2019 | Producer | producer |
| Gente-fied: The Digital Series | 2017 | Producer | executive producer |
| X/Y | 2014 | Producer | producer |
| The Dry Land | 2010 | Producer | executive producer |
| Towards Darkness | 2007 | Producer | executive producer |
| Muertas | 2007 | Producer | executive producer |
| Superstore | 2016–2017 | Soundtrack | performer: "Seasons of Love" |
| Six by Sondheim | 2013 | Soundtrack | performer: "Opening Doors" |
| It's a Disaster | 2012 | Soundtrack | performer: "Blister in The Sun" |
| Ugly Betty | 2008–2010 | Soundtrack | performer: "It's the End of the World as We Know It (And I Feel Fine)" |
| The Hollywood Reporter | 2024 | Self | Self |
| The Oscars Red Carpet Show | 2024 | Self | Self |
| The Oscars | 2024 | Self | Self - Nominee & Presenter |
| The Actor's Side with Pete Hammond TV Series | 2024 | Self | Self - Guest |
| IMDb Originals | 2024 | Self | Self |
| The 30th Annual Screen Actors Guild Awards | 2024 | Self | Self - Nominee & Presenter |
| The Envelope Podcast Series | 2024 | Self | Self - Guest |
| The 49th Annual People's Choice Awards | 2024 | Self | Self - Winner |
| Happy Sad Confused | 2024 | Self | Self - Guest |
| Late Night with Seth Meyers | 2015–2024 | Self | Self - Guest |
| Jimmy Kimmel Live! | 2006–2024 | Self | Self - Guest |
| BBC 100 Women TV Series | 2024 | Self | Self |
| Today | 2014–2024 | Self | Self - Guest |
| The 29th Annual Critics' Choice Awards | 2024 | Self | Self - Honoree & Nominee |
| Critics Choice Celebration of Cinema & Television: Honoring Black, Latino & AAPI Achievements TV Special | 2024 | Self | Self - Honoree |
| The Amanpour Hour | 2024 | Self | Self - Guest |
| Entertainment Tonight | 2006–2024 | Self | Self |
| The Late Show with Stephen Colbert | 2016–2024 | Self | Self - Guest |
| 81st Golden Globe Awards | 2024 | Self | Self - Presenter |
| To Margot's Feet! Margot Robbie, Ryan Gosling, Greta Gerwig & The Barbie Cast FULL Interviews Video | 2023 | Self | Self |
| The Envelope: Oscar Roundtables TV Series | 2023 | Self | Self |
| SAG Foundation Conversations | 2023 | Self | Self |
| Dancing with the Stars | 2023 | Self | Self - Video Message |
| Glamour Women of the Year Awards TV Special | 2023 | Self | Self |
| Hollywood First Look | 2023 | Self | Self |
| The Barbie Story | 2023 | Self | Self - Gloria |
| Access Hollywood | 2008–2023 | Self | Self |
| Good Morning America | 2008–2023 | Self | Self - Guest |
| Dish Nation | 2023 | Self | Self |
| IMDb Interviews | 2019–2023 | Self | Self |
| BuzzFeed Celeb | 2023 | Self | Self |
| The One Show | 2023 | Self | Self - Guest |
| MMTG | 2023 | Self | Self - Guest |
| The Project | 2010–2023 | Self | Self - Actor |
| Fantastic | 2023 | Self | Self - Guest |
| The Kelly Clarkson Show | 2019–2023 | Self | Self - Guest |
| Inspiring America: The 2023 Inspiration List TV Special | 2023 | Self | Self |
| Angel City | 2023 | Self | Self |
| Entertainment Tonight Canada | 2017–2022 | Self | Self |
| Hollywood Insider | 2022 | Self | Self |
| Dare to Lead with Brené Brown Podcast Series | 2021 | Self | Self - Actor & Director (voice) |
| The View | 2005–2021 | Self | Self - Guest Co-Host |
| The Drew Barrymore Show | 2021 | Self | Self - Guest |
| Celebrity Page | 2018–2021 | Self | Self |
| The 73rd Primetime Emmy Awards | 2021 | Self | Self - Presenter |
| En La Sala Podcast Series | 2020 | Self | Self - Guest |
| Every Vote Counts: A Celebration of Democracy TV Special | 2020 | Self | Self - Host |
| The Tonight Show Starring Jimmy Fallon | 2020 | Self | Self - Guest |
| American Voices with Alicia Menendez | 2020 | Self | Self |
| The 72nd Primetime Emmy Awards | 2020 | Self | Self |
| Armchair Expert with Dax Shepard | 2020 | Self | Self |
| Conan | 2020 | Self | Self - Guest |
| CBS Mornings | 2020 | Self | Self - Guest |
| E! Live from the Red Carpet | 2007–2020 | Self | Self |
| The Oscars | 2020 | Self | Self - Audience Member |
| 35th Film Independent Spirit Awards | 2020 | Self | Self - Presenter |
| The 26th Annual Screen Actors Guild Awards | 2020 | Self | Self - Presenter |
| Voice Arts® Awards | 2019 | Self | Self - Winner |
| A Little Late with Lilly Singh | 2019 | Self | Self |
| Peacock Knows Comedy Short | 2019 | Self | Self |
| Superstore: An Evening in Cloud 9 | 2019 | Self | Self |
| WGN Morning News | 2019 | Self | Self |
| Live with Kelly and Mark | 2007–2019 | Self | Self - Guest |
| The 24th Annual Critics' Choice Awards | 2019 | Self | Self - Presenter |
| The ALMAs TV Special | 2018 | Self | Self |
| This Is What Democracy Looks Like | 2018 | Self | Self |
| The Van Jones Show | 2018 | Self | Self - Guest |
| The Daily Show | 2017–2018 | Self | Self - Guest |
| Shine On with Reese | 2018 | Self | Self |
| MAKERS TV Series | 2018 | Self | Self |
| CBS News Sunday Morning with Jane Pauley | 2018 | Self | Self |
| Katy Perry: Will You Be My Witness? | 2017 | Self | Self |
| Harry | 2017 | Self | Self - Guest |
| The Late Late Show with James Corden | 2016–2017 | Self | Self - Guest |
| The Words That Built America | 2017 | Self | Reader - Declaration of Independence |
| Close Up with the Hollywood Reporter | 2017 | Self | Self |
| Katy Perry Live: Witness World Wide | 2017 | Self | Self - Guest |
| Access Daily | 2015–2017 | Self | Self |
| 100 Years | 2017 | Self | |
| Years of Living Dangerously | 2014–2016 | Self | Self |
| The Talk | 2016 | Self | Self - Guest |
| America Divided | 2016 | Self | Self |
| Lip Sync Battle | 2016 | Self | Self - Contestant |
| Lip Sync Battle Preshow | 2016 | Self | Self |
| The Chew | 2016 | Self | Self - Guest |
| Watch What Happens Live with Andy Cohen | 2014–2016 | Self | Self - Guest |
| The 68th Primetime Emmy Awards | 2016 | Self | Self - Presenter |
| The Insider | 2016 | Self | Self |
| Democratic National Convention: Our Fight Song | 2016 | Self | Self |
| Real Time with Bill Maher | 2016 | Self | Self - Guest |
| On Story | 2016 | Self | Self |
| Modern Love Podcast Series | 2016 | Self | Self - Narrator |
| The 4%: Film's Gender Problem | 2016 | Self | Self |
| 21st Annual Critics' Choice Awards | 2016 | Self | Self |
| 2016 Golden Globe Arrivals Special | 2016 | Self | Self |
| 73rd Golden Globe Awards | 2016 | Self | Self - Presenter |
| The Ellen DeGeneres Show | 2006–2015 | Self | Self - Guest |
| The 89th Annual Macy's Thanksgiving Day Parade | 2015 | Self | Self |
| The 30th Annual Imagen Awards TV Special | 2015 | Self | Self |
| Who Do You Think You Are? | 2015 | Self | Self |
| SXSW Flashback 2014 | 2014 | Self | Self |
| Lorraine | 2014 | Self | Self - Guest |
| Loose Women | 2014 | Self | Self - Guest |
| Made in Hollywood | 2010–2014 | Self | Self |
| Fox and Friends | 2014 | Self | Self |
| Sidewalks Entertainment | 2014 | Self | Self - Guest |
| The Late Late Show with Craig Ferguson | 2010–2014 | Self | Self - Guest |
| Nickelodeon Kids Choice Awards 2014 | 2014 | Self | Self |
| The Wendy Williams Show | 2014 | Self | Self - Guest |
| Six by Sondheim | 2013 | Self | Mary |
| West Wing Week | 2013 | Self | Self |
| Anderson Live | 2012 | Self | Self |
| Half the Sky | 2012 | Self | Self |
| 2012 ALMA Awards | 2012 | Self | Self |
| This Morning | 2011 | Self | Self - Guest |
| Independent Lens | 2003–2011 | Self | Self - Host |
| The Latino List | 2011 | Self | Self |
| Chris Moyles Quiz Night | 2011 | Self | Self - Guest |
| How to Train Your Dragon: Viking-Sized Cast | 2010 | Self | Self |
| In the House with Peter Bart & Peter Guber | 2010 | Self | Self |
| Lopez Tonight | 2010 | Self | Self - Guest |
| Moving Pictures Live! | 2010 | Self | Self |
| HBO First Look | 2002–2010 | Self | Self |
| Jean-Michel Basquiat: The Radiant Child | 2010 | Self | Self - Hostess |
| William S. Burroughs: A Man Within | 2010 | Self | Self - Host |
| 2009 Golden Globe Awards Red Carpet Special | 2009 | Self | Self |
| Nickelodeon Kids' Choice Awards 2009 | 2009 | Self | Self |
| 15th Annual Screen Actors Guild Awards | 2009 | Self | Self - Nominee |
| Golden Globe Awards | 2009 | Self | Self - Nominee |
| Rachael Ray | 2008 | Self | Self - Guest |
| TV Guide Live at the Emmy Awards | 2008 | Self | Self |
| The 60th Primetime Emmy Awards | 2008 | Self | Self - Presenter |
| 2008 ALMA Awards | 2008 | Self | Self |
| Stand Up to Cancer | 2008 | Self | Self |
| Late Night with Conan O'Brien | 2007–2008 | Self | Self - Guest |
| Extra | 2008 | Self | Self |
| Late Show with David Letterman | 2007–2008 | Self | Self - Guest |
| Nickelodeon Kids' Choice Awards 2008 | 2008 | Self | Self |
| Up Close with Carrie Keagan | 2008 | Self | Self - Guest |
| The Tonight Show with Jay Leno | 2006–2008 | Self | Self - Guest |
| 39th NAACP Image Awards | 2008 | Self | Self |
| Speechless | 2008 | Self | Self |
| The 9th Annual Family Television Awards TV Special | 2007 | Self | Self |
| Infanity | 2007 | Self | Self |
| The 59th Annual Primetime Emmy Awards | 2007 | Self | Self - Presenter & Winner |
| 2007 Primetime Creative Arts Emmy Awards | 2007 | Self | Self |
| The Teen Choice Awards 2007 | 2007 | Self | Self - Presenter & Winner |
| Becoming Ugly: A New Face for Television Video | 2007 | Self | Self |
| Xposé | 2007 | Self | Self |
| 38th NAACP Image Awards | 2007 | Self | Self |
| Film Independent's 2007 Spirit Awards | 2007 | Self | Self - Presenter |
| 13th Annual Screen Actors Guild Awards | 2007 | Self | Self - Winner |
| The 64th Annual Golden Globe Awards | 2007 | Self | Self - Winner |
| The Oprah Winfrey Show | 2006 | Self | Self - Guest |
| 2006 ALMA Awards | 2006 | Self | Self |
| Planet H2O TV Mini Series | 2006 | Self | Self |
| Young Hollywood Awards | 2005 | Self | Self |
| The Drop | 2005 | Self | Self |
| Nickelodeon Kids' Choice Awards '05 | 2005 | Self | Self |
| The Sharon Osbourne Show | 2004 | Self | Self - Guest |
| Express Yourself | 2002–2003 | Self | Self |
| Disney Channel: Express Yourself - Halloween Video | 2003 | Self | Self |
| The 2003 IFP Independent Spirit Awards | 2003 | Self | Self |
| Somos Grandes TV Series | 2024 | Archive Footage | Self (archive footage) |
| The Project | 2024 | Archive Footage | Self - Actor (archive footage) |
| Entertainment Tonight | 2014–2024 | Archive Footage | Self (archive footage) |
| American Voices with Alicia Menendez | 2024 | Archive Footage | Self (archive footage) |
| Rita Moreno: Just a Girl Who Decided to Go for It | 2021 | Archive Footage | Self (archive footage) |
| Inside Edition Weekend | 2020 | Archive Footage | Self (archive footage) |
| Access Hollywood | 2019–2020 | Archive Footage | Self (archive footage) |
| History 101 | 2020 | Archive Footage | Self (archive footage) |
| Celebrity Page | 2018 | Archive Footage | Self (archive footage) |
| Inside Edition | 2017 | Archive Footage | Self (archive footage) |
| The Insider | 2016 | Archive Footage | Self (archive footage) |
| The Late Show with Stephen Colbert | 2016 | Archive Footage | Self (archive footage) |
| CBS News Sunday Morning with Jane Pauley | 2008 | Archive Footage | Betty Suarez (archive footage) |
| The Beautiful World of Ugly Betty | 2007 | Archive Footage | Betty Suarez (archive footage) |
| The Beauty of Ugly Betty | 2007 | Archive Footage | Betty Suarez (archive footage) |