| A Breed Apart | 2025 | Actress | Hayden Hearst |
| Until Dawn | 2024 | Actress | Samantha (voice) |
| Amber Alert | 2024 | Actress | Jaq |
| Scream VI | 2023 | Actress | Kirby Reed |
| Nashville | 2012–2018 | Actress | Juliette Barnes |
| Custody | 2016 | Actress | Ally |
| Heroes Reborn | 2015–2016 | Actress | Claire Bennet (uncredited) |
| Until Dawn | 2015 | Actress | Samantha (voice) |
| Jason Aldean: 1994 | 2013 | Actress | Hayden Panettiere |
| The Forger | 2012 | Actress | Amber Felter |
| Kingdom Hearts 3D: Dream Drop Distance | 2012 | Actress | Xion (English version, voice) |
| Scream 4 | 2011 | Actress | Kirby Reed |
| Hoodwinked Too! Hood vs. Evil | 2011 | Actress | Red Riding Hood (voice) |
| Amanda Knox | 2011 | Actress | Amanda Knox |
| American Dad! | 2010 | Actress | Ashley (voice) |
| Alpha and Omega | 2010 | Actress | Kate (voice) |
| Joshua Radin: I'd Rather Be with You | 2010 | Actress | Joshua's Girlfriend |
| Heroes | 2006–2010 | Actress | Claire Bennet |
| Kingdom Hearts: Birth by Sleep | 2010 | Actress | Kairi |
| I Love You, Beth Cooper | 2009 | Actress | Beth Cooper |
| Scooby-Doo and the Goblin King | 2008 | Actress | Fairy Princess Willow (voice) |
| Fireflies in the Garden | 2008 | Actress | Young Jane Lawrence |
| Robot Chicken | 2007 | Actress | Cheetara |
| Kingdom Hearts II: Final Mix+ | 2007 | Actress | Kairi (English version, voice) |
| Shanghai Kiss | 2007 | Actress | Adelaide Bourbon |
| Skater Boys | 2006 | Actress | Kassidy Parker #2 |
| Bring It on: All or Nothing | 2006 | Actress | Britney |
| The Architect | 2006 | Actress | Christina Waters |
| The Good Student | 2006 | Actress | Ally Palmer |
| Commander in Chief | 2006 | Actress | Stacy |
| Kingdom Hearts II | 2005 | Actress | Kairi (English version, voice) |
| Malcolm in the Middle | 2003–2005 | Actress | Jessica |
| Ice Princess | 2005 | Actress | Gen Harwood |
| Lies My Mother Told Me | 2005 | Actress | Haylei Sims |
| Law & Order: Special Victims Unit | 2001–2005 | Actress | Angela Agnelli |
| Racing Stripes | 2005 | Actress | Channing Walsh |
| The Dust Factory | 2004 | Actress | Melanie Lewis |
| Tiger Cruise | 2004 | Actress | Maddie Dolan |
| Raising Helen | 2004 | Actress | Audrey Davis |
| Fillmore! | 2004 | Actress | Yumi (voice, as Hayden Panitterie) |
| Kingdom Hearts | 2003 | Actress | Kairi (voice) |
| Normal | 2003 | Actress | Patty Ann Applewood |
| The Mark of Kri | 2002 | Actress | Tati (voice) |
| Ally McBeal | 2002 | Actress | Maddie Harrington |
| Kingdom Hearts | 2002 | Actress | Kairi (English version, voice) |
| Chestnut Hill | 2001 | Actress | Molly Eastman |
| Joe Somebody | 2001 | Actress | Natalie Scheffer |
| The Affair of the Necklace | 2001 | Actress | Young Jeanne |
| Guiding Light | 1997–2000 | Actress | Lizzie Spaulding |
| Remember the Titans | 2000 | Actress | Sheryl Yoast |
| Dinosaur | 2000 | Actress | Suri (voice) |
| Too Rich: The Secret Life of Doris Duke | 1999 | Actress | Young Doris Duke |
| If You Believe | 1999 | Actress | Suzie |
| Touched by an Angel | 1999 | Actress | Diana |
| Message in a Bottle | 1999 | Actress | Girl On Sinking Boat |
| A Bug's Life: The Video Game | 1998 | Actress | Dot (voice) |
| A Bug's Life | 1998 | Actress | Dot (voice) |
| A Bug's Life | 1998 | Actress | Dot (voice, as Hayden Panettier) |
| A Will of Their Own | 1998 | Actress | |
| The Object of My Affection | 1998 | Actress | Mermaid |
| One Life to Live | 1994–1997 | Actress | Sarah Roberts |
| Unhappily Ever After | 1997 | Actress | Little Girl |
| Wendy's Chicken Nuggets Commercial | 1996 | Actress | Girl |
| How Do You Spell God? | 1996 | Actress | Megan Blackwood |
| Aliens in the Family | 1996 | Actress | Audrey |
| Amber Alert | 2024 | Producer | executive producer |
| H.M.S.: White Coat | 2010 | Producer | executive producer |
| Tiger Cruise | 2004 | Music Department | composer: song "My Hero is You" |
| Red Table Talk | 2022 | Thanks | special thanks |
| Scream | 2022 | Thanks | special thanks |
| Nashville: The Whole Story | 2013 | Thanks | thanks |
| Heroes: Countdown to the Premiere | 2008 | Thanks | special thanks |
| Nashville | 2012–2016 | Soundtrack | performer: "Boomtown" |
| Nashville: On the Record | 2014 | Soundtrack | performer: "Nothing In This World", "Don't Put Dirt On My Grave Just Yet", "A Life That's Good" |
| Hoodwinked Too! Hood vs. Evil | 2011 | Soundtrack | performer: "I Can Do It Alone", "Inseparable" |
| I Love You, Beth Cooper | 2009 | Soundtrack | performer: "School's Out" |
| Shanghai Kiss | 2007 | Soundtrack | performer: "Hang On Little Tomato", "Home" |
| Bridge to Terabithia | 2007 | Soundtrack | performer: "Try" |
| Cinderella 3: A Twist in Time | 2007 | Soundtrack | performer: "I Still Believe" |
| Ice Princess | 2005 | Soundtrack | performer: "I Fly" |
| The Dust Factory | 2004 | Soundtrack | performer: "Someone Like You" |
| Tiger Cruise | 2004 | Soundtrack | performer: "My Hero Is You" |
| Made in Hollywood | 2011–2024 | Self | Self |
| FilmUpdates TV Series | 2024 | Self | Self |
| Us Weekly: YouTube Channel TV Series | 2024 | Self | Self |
| Today | 2007–2024 | Self | Self - Guest |
| People: YouTube Channel TV Series | 2024 | Self | Self |
| Leute heute | 2023 | Self | Self |
| Entertainment Tonight | 2007–2023 | Self | Self |
| The View | 2007–2023 | Self | Self |
| Access Hollywood | 2007–2023 | Self | Self |
| Good Morning America | 2004–2023 | Self | Self - Guest |
| Red Table Talk | 2022 | Self | Self |
| HBO Boxing | 2013–2017 | Self | Self - Audience Member |
| The Talk | 2017 | Self | Self |
| Access Daily | 2015–2017 | Self | Self |
| The Late Late Show with James Corden | 2017 | Self | Self |
| Harry | 2017 | Self | Self |
| The Late Show with Stephen Colbert | 2017 | Self | Self |
| Style Code Live | 2017 | Self | Self |
| Live with Kelly and Mark | 2007–2017 | Self | Self - Guest |
| Lip Sync Battle | 2016 | Self | Self - Competitor |
| 21st Annual Critics' Choice Awards | 2016 | Self | Self |
| Chopped Junior | 2016 | Self | Self - Judge |
| Sky Sports World Championship Boxing | 2015 | Self | Self |
| The Insider | 2015 | Self | Self |
| The Chew | 2012–2015 | Self | Self - Guest |
| The Meredith Vieira Show | 2015 | Self | Self - Guest |
| E! Live from the Red Carpet | 2007–2014 | Self | Self |
| The 66th Primetime Emmy Awards | 2014 | Self | Self - Presenter |
| E! News | 2014 | Self | Self |
| Nashville: On the Record | 2014 | Self | Self |
| The Late Late Show with Craig Ferguson | 2014 | Self | Self - Guest |
| 2014 Golden Globe Arrivals Special | 2014 | Self | Self - Interviewee |
| 71st Golden Globe Awards | 2014 | Self | Self - Nominee (uncredited) |
| CMT Artists of the Year | 2013 | Self | Self |
| The Ellen DeGeneres Show | 2006–2013 | Self | Self - Guest |
| Rachael Ray | 2011–2013 | Self | Self - Guest |
| Evening Urgant | 2013 | Self | Self |
| Late Show with David Letterman | 2007–2013 | Self | Self - Guest |
| The Graham Norton Show | 2013 | Self | Self - Guest |
| 2013 Billboard Music Awards | 2013 | Self | Self - Presenter |
| The Factor | 2013 | Self | Self - Guest (segment "Watters' World") |
| Late Night with Jimmy Fallon | 2013 | Self | Self - Guest |
| Hayden Panettiere: Fame | 2013 | Self | Self |
| 70th Golden Globe Awards | 2013 | Self | Self - Nominee |
| Jimmy Kimmel Live! | 2009–2013 | Self | Self - Guest (segment "Mean Tweets") |
| Hayden Panettiere: Telescope | 2012 | Self | Self |
| The 40th Anniversary American Music Awards | 2012 | Self | Self |
| Chelsea Lately | 2011–2012 | Self | Self - Guest |
| Big Morning Buzz Live | 2012 | Self | Self - Guest |
| 20/20 | 2012 | Self | Self - Actress (segment "The Greatest Women of Country Music") |
| The 64th Primetime Emmy Awards | 2012 | Self | Self - Presenter |
| Project Runway | 2012 | Self | Self - Guest Judge |
| Teen Choice Awards 2012 | 2012 | Self | Self - Presenter |
| Whale Entanglements: A Deadly Problem Short | 2012 | Self | Self |
| Punk'd | 2006–2012 | Self | Self |
| Minds in the Water | 2011 | Self | |
| MTV EMA Belfast 2011 | 2011 | Self | Self - Presenter |
| The Making of 'Scream 4' | 2011 | Self | Self |
| SAT.1-Frühstücksfernsehen | 2011 | Self | Self |
| Hayden Panettiere: I Can Do It Alone | 2011 | Self | Self |
| Film Fiend | 2011 | Self | Self - Guest |
| Kurier Romy 2011 | 2011 | Self | Self - Presenter |
| Conan | 2011 | Self | Self - Guest |
| Up Close with Carrie Keagan | 2009–2011 | Self | Self - Guest |
| The Tonight Show with Jay Leno | 1996–2011 | Self | Self - Guest |
| Celebrity Beach Bowl 2011 TV Special | 2011 | Self | Self |
| TeenNick Halo Awards | 2010 | Self | Self |
| Ask Rhod Gilbert | 2010 | Self | Self |
| Breakfast | 2010 | Self | Self - Guest |
| The Xtra Factor | 2010 | Self | Self |
| The 2010 World Music Awards | 2010 | Self | Self - Host |
| 2010 CMT Music Awards | 2010 | Self | Self |
| taff | 2010 | Self | Self - segment (World music Awards) |
| The Cove: My Friend is... | 2010 | Self | Self |
| In Character with... | 2009 | Self | Self |
| Proudly We Stand: The Inauguration of Barack Obama | 2009 | Self | Self |
| TeenNick Halo Awards | 2009 | Self | Self |
| The 61st Primetime Emmy Awards | 2009 | Self | Self - Presenter |
| The Teen Choice Awards 2009 | 2009 | Self | Self - Winner & Presenter |
| Spike's Guys Choice | 2009 | Self | Self |
| 2009 MTV Movie Awards | 2009 | Self | Self - Presenter |
| The Cove | 2009 | Self | Self - Whateman Foundation |
| Hollywood 411 | 2009 | Self | Self |
| Nickelodeon Kids' Choice Awards 2009 | 2009 | Self | Self |
| Golden Globe Awards | 2009 | Self | Self - Presenter |
| Hayden Panettiere: Wake Up Call | 2008 | Self | Self |
| Heroes Report | 2008 | Self | Self |
| The 22nd Annual Genesis Awards TV Special | 2008 | Self | Self |
| Heroes Unmasked | 2007–2008 | Self | Self |
| 2007 Vail Film Festival Short | 2008 | Self | Self |
| Heroes: Countdown to the Premiere | 2008 | Self | Self |
| The 60th Primetime Emmy Awards | 2008 | Self | Self - Presenter |
| Séries express | 2008 | Self | Self |
| The Teen Choice Awards 2008 | 2008 | Self | Self - Winner |
| Nickelodeon Kids' Choice Awards 2008 | 2008 | Self | Self |
| Larry King Live | 2008 | Self | Self - Guest |
| Christmas in Rockefeller Center | 2007 | Self | Self |
| The Hills | 2007 | Self | Self (uncredited) |
| Scream Awards 2007 | 2007 | Self | Self |
| In Search of Puppy Love | 2007 | Self | Self |
| The 59th Annual Primetime Emmy Awards | 2007 | Self | Self - Presenter |
| MTV VMA Pre Show Royale | 2007 | Self | Self |
| 2007 MTV Video Music Awards | 2007 | Self | Self |
| Richard & Judy | 2007 | Self | Self - Guest |
| A Capitol Fourth | 2007 | Self | Self |
| The Morning Show with Mike & Juliet | 2007 | Self | Self - Guest |
| Descifrando héroes | 2007 | Self | Self |
| Nickelodeon Kids' Choice Awards '07 | 2007 | Self | Self |
| Total Request Live | 2007 | Self | Self |
| Late Night with Conan O'Brien | 2007 | Self | Self - Guest |
| The 64th Annual Golden Globe Awards | 2007 | Self | Self - Presenter |
| The 33rd Annual People's Choice Awards | 2007 | Self | Self |
| MTV Goes Gold: New Year's Eve 2007 TV Special | 2007 | Self | Self - Guest |
| Hayden Panettiere: I Still Believe | 2006 | Self | Self |
| New Year's Eve with Carson Daly TV Special | 2006 | Self | Self |
| VH1 Big in 06 Awards | 2006 | Self | Self |
| 75th Annual Hollywood Christmas Parade | 2006 | Self | Self |
| Infanity | 2006 | Self | Self |
| Last Call with Carson Daly | 2006 | Self | Self - Guest |
| Hayden Panettiere: I Fly | 2005 | Self | Self |
| The Voices of Kingdom Hearts II TV Special | 2005 | Self | Self |
| Young Hollywood Awards | 2005 | Self | Self |
| The Teen Choice Awards 2005 | 2005 | Self | Self |
| Dennis Miller | 2005 | Self | Self |
| The Tony Danza Show | 2005 | Self | Self - Guest |
| Hayden Panettiere & Watt White: Someone Like You | 2004 | Self | Self |
| Hayden Panettiere: My Hero is You | 2004 | Self | Self |
| On the Set: Raising Helen | 2004 | Self | Self |
| G-Phoria | 2003 | Self | Self |
| The Rosie O'Donnell Show | 2000 | Self | Self - Guest |
| The 25th Annual Daytime Emmy Awards | 1998 | Self | Self - Co-Presenter: Outstanding Pre-School Children's Series |
| Entertainment Tonight | 2016–2023 | Archive Footage | Self (archive footage) |
| Justin Bieber: The New Me | 2021 | Archive Footage | Self (archive footage) |
| Celebrity Page | 2015–2020 | Archive Footage | Self (archive footage) |
| Access Hollywood | 2017 | Archive Footage | Self (archive footage) |
| Extra | 2016 | Archive Footage | Self (archive footage) |
| Heroes Reborn: Dark Matters | 2015 | Archive Footage | Claire Bennet (archive footage) |
| Inside Edition | 2014 | Archive Footage | Self (archive footage) |
| The Insider | 2014 | Archive Footage | Self (archive footage) |
| Chelsea Lately | 2013–2014 | Archive Footage | Juliette Barnes in 'Nashville' |
| Live with Kelly and Mark | 2013–2014 | Archive Footage | Self (archive footage) |
| taff | 2013 | Archive Footage | Self (archive footage) |
| The Graham Norton Show | 2013 | Archive Footage | Self (archive footage) |
| Klitschko | 2011 | Archive Footage | Self (archive footage) |
| I Love You, Beth Cooper: Alternate Ending | 2009 | Archive Footage | Beth Cooper (archive footage) |
| Almost Famous II | 2009 | Archive Footage | (archive footage) |
| Heroes Unmasked | 2007–2008 | Archive Footage | Claire Bennet |
| Heroes | 2007–2008 | Archive Footage | Claire Bennet (archive footage, uncredited) |
| Jo, heroi TV Movie | 2007 | Archive Footage | Claire Bennet (archive footage) |
| Kingdom Hearts HD 1.5 + 2.5 Remix | 2017 | Archive Sound | Kairi (archive footage) |
| Kingdom Hearts HD 2.8 Final Chapter Prologue | 2017 | Archive Sound | Xion (archive footage) |
| Kingdom Hearts HD 2.5 Remix | 2014 | Archive Sound | Kairi (archive footage) |
| Kingdom Hearts HD 1.5 Remix | 2013 | Archive Sound | Kairi (archive footage) |