| The Last of Us | 2025 | Actress | Dina |
| Alien: Romulus | 2024 | Actress | Kay |
| Turtles All the Way Down | 2024 | Actress | Aza Holmes |
| Rock, Paper, Scissors | 2024 | Actress | The Susan (voice) |
| Madame Web | 2024 | Actress | Anya Corazón |
| Migration | 2023 | Actress | Kim (voice) |
| Rosaline | 2022 | Actress | Juliet |
| Father of the Bride | 2022 | Actress | Cora Herrera |
| Spirit & Friends | 2022 | Actress | Lucky (voice) |
| Maya and the Three | 2021 | Actress | Widow Queen (voice) |
| Sweet Girl | 2021 | Actress | Rachel Cooper |
| DreamWorks Spirit Lucky's Big Adventure | 2021 | Actress | Lucky (English version, voice) |
| Spirit Untamed | 2021 | Actress | Lucky Prescott (voice) |
| Isabela Merced & Danna Paola: Don't Go | 2020 | Actress | Isabela Merced |
| Isabela Merced: Apocalipsis | 2020 | Actress | Isabela Merced |
| Let It Snow | 2019 | Actress | Julie |
| Isabela Merced: PAPI | 2019 | Actress | Isabela Merced |
| Dora and the Lost City of Gold | 2019 | Actress | Dora (as Isabela Moner) |
| Isabela Moner: I'll Stay (Lyric Version) | 2018 | Actress | Isabela Moner (as Isabela Moner) |
| Matt Hunter & Isabela Moner: Lista De Espera | 2018 | Actress | Isabela Moner (as Isabela Moner) |
| Instant Family | 2018 | Actress | Lizzy (as Isabela Moner) |
| Sicario: Day of the Soldado | 2018 | Actress | Isabel Reyes (as Isabela Moner) |
| The Nut Job 2: Nutty by Nature | 2017 | Actress | Heather (voice, as Isabela Moner) |
| Transformers: The Last Knight | 2017 | Actress | Izabella (as Isabela Moner) |
| Dora and Friends: Into the City! | 2014–2017 | Actress | Kate |
| Kingdom Hearts HD 2.8 Final Chapter Prologue | 2017 | Actress | Ava (English version, voice, as Isabela Moner) |
| Legends of the Hidden Temple | 2016 | Actress | Sadie (as Isabela Moner) |
| Middle School: The Worst Years of My Life | 2016 | Actress | Jeanne (as Isabela Moner) |
| 100 Things to Do Before High School | 2015–2016 | Actress | CJ Martin (as Isabela Moner) |
| Isabela Moner: Wonderwall | 2015 | Actress | Isabela Moner (as Isabela Moner) |
| Isabela Moner: Count on Me | 2015 | Actress | Isabela Moner (as Isabela Moner) |
| Isabela Moner: Every Girl | 2015 | Actress | Isabela Moner (as Isabela Moner) |
| Isabela Moner: Halo | 2015 | Actress | Isabela Moner (as Isabela Moner) |
| Nickelodeon's Ho Ho Holiday Special | 2015 | Actress | Isabela Moner (as Isabela Moner) |
| Fearleaders | 2015 | Actress | Braaainsley (as Isabela Moner) |
| Isabela Moner: Dream About Me | 2015 | Actress | Isabela Moner (as Isabela Moner) |
| Splitting Adam | 2015 | Actress | Lori Collins (as Isabela Moner) |
| 100 Things to Do Before High School | 2014 | Actress | CJ Martin (as Isabela Moner) |
| Growing Up Fisher | 2014 | Actress | Jenny (as Isabela Moner) |
| The House That Jack Built | 2013 | Actress | Young Nadia (as Isabela Moner) |
| 100 Things to Do Before High School | 2015–2016 | Music Department | performer: "Brand New Day" (as Isabela Moner) |
| Spirit Untamed | 2021 | Soundtrack | performer: "Better with You (From Spirit Untamed)", "Fearless (Valiente Duet) [From Spirit Untamed]" |
| Dora and the Lost City of Gold | 2019 | Soundtrack | performer: "Backpack Song", "Map Song", "Poo Hole Song", "Freak Out Song" |
| Instant Family | 2018 | Soundtrack | performer: "I'll Stay" |
| Fearleaders | 2015 | Soundtrack | performer: "Fearleaders" |
| The Kelly Clarkson Show | 2019–2025 | Self | Self |
| The Tonight Show Starring Jimmy Fallon | 2025 | Self | Self |
| Creator to Creator Podcast Series | 2025 | Self | Self |
| LADbible Entertainment TV Series | 2025 | Self | Self |
| La boîte à questions | 2025 | Self | Self |
| IMDb on the Scene | 2024–2025 | Self | Self - Guest |
| eTalk Daily | 2025 | Self | Self |
| IMDb Originals | 2025 | Self | Self - Guest |
| Casting the Web Video | 2024 | Self | Self |
| Future Vision Video | 2024 | Self | Self |
| ABC News Breakfast | 2024 | Self | Self - Guest |
| Variety Studio | 2024 | Self | Self - Guest |
| Made in Hollywood | 2017–2024 | Self | Self |
| Entertainment Tonight | 2016–2024 | Self | Self |
| IMDb Interviews | 2022–2024 | Self | Self - Guest |
| Ari Global show | 2022 | Self | Self - Guest |
| Cultura Shock | 2022 | Self | Self - Guest |
| Hollywood First Look | 2022 | Self | Self |
| Hollywood on Set | 2021 | Self | Self |
| The IMDb Show | 2021 | Self | Self - Guest |
| 8 Bit Melody Challenge TV Series | 2020 | Self | Self |
| #Graduation2020: Facebook and Instagram Celebrate the Class of 2020 | 2020 | Self | Self |
| #KidsTogether: The Nickelodeon Town Hall | 2020 | Self | Self |
| 32nd Hispanic Heritage Awards TV Special | 2019 | Self | Self |
| Orange Carpet Special Edition | 2019 | Self | Self - Host |
| Celebrity Page | 2017–2019 | Self | Self (as Isabela Moner) |
| GMA3: What You Need to Know | 2019 | Self | Self (as Isabela Moner) |
| Today | 2018–2019 | Self | Self - Guest (as Isabela Moner) |
| Live with Kelly and Mark | 2019 | Self | Self - Guest (as Isabela Moner) |
| Great Day Washington TV Series | 2019 | Self | Self - Actress, Dora and the Lost City of Gold (as Isabela Moner) |
| Entertainment Tonight Canada | 2019 | Self | Self in Las Vegas (as Isabela Moner) |
| Nickelodeon Kids' Choice Awards 2019 | 2019 | Self | Self - Presenter (as Isabela Moner) |
| The Talk | 2018 | Self | Self - Guest (as Isabela Moner) |
| The Assassin and the Soldier: The Cast and Characters | 2018 | Self | Self (as Isabela Moner) |
| Made in Hollywood: Teen Edition | 2017 | Self | Self (as Isabela Moner) |
| Transformers 5: Motors and Magic | 2017 | Self | Self (as Isabela Moner) |
| Teen Choice Awards 2017 | 2017 | Self | Self - Audience Member (uncredited) |
| Dish Nation | 2017 | Self | Self (as Isabela Moner) |
| Access Hollywood | 2017 | Self | Self (as Isabela Moner) |
| Extra | 2017 | Self | Self (as Isabela Moner) |
| Home & Family | 2017 | Self | Self (as Isabela Moner) |
| Access Daily | 2017 | Self | Self (as Isabela Moner) |
| The Strip Live TV Series | 2017 | Self | Self - Guest |
| Nickelodeon Kids' Choice Awards 2017 | 2017 | Self | Self - Presenter (as Isabela Moner) |
| Nickelodeon HALO Awards 2016 | 2016 | Self | Self (as Isabela Moner) |
| 31st Annual Imagen Awards | 2016 | Self | Self (as Isabela Moner) |
| Justine Magazine: Isabela Moner's Photoshoot and Interview for "Legends of the Hidden Temple"! Video | 2016 | Self | Self (as Isabela Moner) |
| Alexis Joy VIP Access | 2015–2016 | Self | Self (as Isabela Moner) |
| The 30th Annual Imagen Awards TV Special | 2015 | Self | Self (as Isabela Moner) |
| Nickelodeon Kids' Choice Sports 2015 | 2015 | Self | Self (as Isabela Moner) |
| Piper's Picks TV | 2015 | Self | Self - Guest (as Isabela Moner) |
| The Next Big Thing: NY | 2012 | Self | Self (as Isabela Moner) |
| SLAYER NATION LIVE! TV Series | 2025 | Archive Footage | Self (archive footage) |
| Alien, terreur sur grand écran | 2025 | Archive Footage | Self (archive footage) |
| Latino Slant TV Series | 2024 | Archive Footage | Self (archive footage) |
| ABC News Breakfast | 2024 | Archive Footage | Self - Actor, Alien: Romulus (archive footage, uncredited) |
| Disparu | 2024 | Archive Footage | Self (archive footage) |
| Tyrone Magnus | 2024 | Archive Footage | Self (archive footage) |
| Nerdrotic | 2024 | Archive Footage | Self (archive footage) |
| Entertainment Tonight | 2016–2024 | Archive Footage | Self (archive footage) |