| The Choir | 2013 | Director | Director |
| The Misadventures of Awkward Black Girl | 2011–2023 | Director | Director |
| Rap Sh!t | 2022–2023 | Writer | created by |
| Insecure | 2016–2021 | Writer | created by |
| The Choir | 2013–2015 | Writer | Writer |
| Black Twitter Screening Short | 2014 | Writer | Writer |
| The Misadventures of Awkward Black Girl | 2012 | Writer | Writer |
| Black Mirror | 2025 | Actress | Brandy |
| Young Love | 2023 | Actress | Angela Young (voice) |
| American Fiction | 2023 | Actress | Sintara Golden |
| Barbie | 2023 | Actress | Barbie |
| Spider-Man: Across the Spider-Verse | 2023 | Actress | Jessica Drew (voice) |
| A Black Lady Sketch Show | 2019–2023 | Actress | Trina |
| Sherman's Showcase | 2022 | Actress | Iman |
| Send Help | 2022 | Actress | Casting Director |
| Vengeance | 2022 | Actress | Eloise |
| Roar | 2022 | Actress | Wanda Shepard |
| Insecure | 2016–2021 | Actress | Issa Dee |
| Coastal Elites | 2020 | Actress | Callie Josephson |
| The Lovebirds | 2020 | Actress | Leilani |
| D Smoke & SiR: Lights On Music Video | 2020 | Actress | |
| #BlackAF | 2020 | Actress | Issa Rae |
| The Photograph | 2020 | Actress | Mae Morton |
| Hair Love | 2019 | Actress | Natural Hair Vlogger |
| Little | 2019 | Actress | April Williams |
| BoJack Horseman | 2018 | Actress | Dr. Indira (voice) |
| The Hate U Give | 2018 | Actress | April Ofrah |
| Drake: Nice for What | 2018 | Actress | Issa Rae |
| Jay-Z: Moonlight | 2017 | Actress | Rachel |
| A Bitter Lime | 2015 | Actress | Jane Johnson |
| Protect and Serve | 2015 | Actress | Police Recruit |
| Rubberhead | 2014 | Actress | Bride 2 (segment "Absorption") |
| Little Horribles Short | 2013 | Actress | |
| Pharrell Williams: Happy | 2013 | Actress | Dancer |
| Instacurity | 2013 | Actress | Issa |
| My Roommate the | 2013 | Actress | J |
| Orange Is the New Black and Sexy | 2013 | Actress | Taystee |
| True Friendship Society TV Series | 2013 | Actress | Mama Moth |
| Little Horribles | 2013 | Actress | Best Friend |
| The Number | 2012–2013 | Actress | Lisa |
| The Misadventures of Awkward Black Girl | 2011–2013 | Actress | J |
| The Couple | 2012 | Actress | Lisa |
| Seen & Heard TV Mini Series | 2025 | Producer | executive producer |
| One of Them Days | 2025 | Producer | producer (p.g.a.) |
| Grief Retreat Short | 2024 | Producer | executive producer |
| Gray Matter | 2023 | Producer | executive producer |
| Project Greenlight: A New Generation | 2023 | Producer | executive producer |
| Rap Sh!t | 2022–2023 | Producer | executive producer |
| Chat Sh!t: The Official Rap Sh!t Podcast | 2022 | Producer | executive producer |
| A Black Lady Sketch Show | 2019–2022 | Producer | executive producer |
| Insecure | 2016–2021 | Producer | executive producer |
| As Heard on Insecure Video | 2021 | Producer | executive producer |
| Sweet Life: Los Angeles | 2021 | Producer | executive producer |
| The Lovebirds | 2020 | Producer | executive producer |
| Dark City Beneath the Beat | 2020 | Producer | producer |
| The Photograph | 2020 | Producer | executive producer |
| Insecure: Due North | 2017 | Producer | executive producer |
| Killing Lazarus | 2016 | Producer | producer |
| Get Your Life | 2015–2017 | Producer | executive producer |
| First | 2014–2015 | Producer | co-executive producer |
| The Choir | 2013–2015 | Producer | executive producer |
| Protect and Serve | 2015 | Producer | executive producer |
| Words with Girls TV Movie | 2014 | Producer | executive producer |
| Bleach | 2014 | Producer | executive producer |
| So Jaded | 2014 | Producer | executive producer |
| Hard Times Video | 2014 | Producer | executive producer |
| Roomieloverfriends | 2013–2014 | Producer | executive producer |
| Black Actress | 2013 | Producer | producer |
| Inside Web Series | 2013 | Producer | executive producer |
| Little Horribles | 2013 | Producer | executive producer |
| How Men Become Dogs | 2013 | Producer | executive producer |
| The Misadventures of Awkward Black Girl | 2013 | Producer | producer |
| M.O. Diaries | 2012 | Producer | executive producer |
| Queen & Slim | 2019 | Thanks | filmmakers wish to thank |
| Drty Diana | 2015 | Thanks | very special thanks |
| Ryan & Ruby | 2014 | Thanks | special thanks |
| The United Colors of Amani TV Series | 2013 | Thanks | special thanks |
| How Men Become Dogs | 2013 | Thanks | special thanks |
| The Misadventures of Awkward Black Girl | 2012 | Soundtrack | performer: "Freestyle" (uncredited) |
| IMO with Michelle Obama & Craig Robinson Podcast Series | 2025 | Self | Self - Guest |
| No Taste Like Home with Antoni Porowski | 2025 | Self | Self |
| Seen & Heard TV Mini Series | 2025 | Self | |
| Hot Ones Versus | 2025 | Self | Self |
| Entertainment Tonight | 2019–2025 | Self | Self |
| Sherri | 2023–2025 | Self | Self |
| Impolitic with John Heilemann Podcast Series | 2024 | Self | Self |
| IMDb on the Scene | 2024 | Self | Self |
| The Oscars | 2024 | Self | Self - Presenter |
| The 30th Annual Screen Actors Guild Awards | 2024 | Self | Self - Nominee & Presenter |
| CBS News Sunday Morning with Jane Pauley | 2024 | Self | Self |
| 81st Golden Globe Awards | 2024 | Self | Self - Presenter |
| To Margot's Feet! Margot Robbie, Ryan Gosling, Greta Gerwig & The Barbie Cast FULL Interviews Video | 2023 | Self | Self |
| The View | 2016–2023 | Self | Self - Guest |
| Access Hollywood | 2020–2023 | Self | Self |
| Watch What Happens Live with Andy Cohen | 2017–2023 | Self | Self - Guest |
| The Tonight Show Starring Jimmy Fallon | 2016–2023 | Self | Self - Guest |
| Today | 2018–2023 | Self | Self - Guest |
| Raising a Hero Video | 2023 | Self | Self |
| Your Friendly Neighborhood Spider-Cast Video | 2023 | Self | Self |
| Spider-Man: Across the Spider-Verse - Creating the Ultimate Spider-Man Movie Video | 2023 | Self | Self |
| Across the Comics-Verse Video | 2023 | Self | Self |
| The Barbie Story | 2023 | Self | Self - Unlikely President Barbie |
| GMA3: What You Need to Know | 2021–2023 | Self | Self |
| Hart to Heart | 2023 | Self | Self - Guest |
| Good Morning America | 2016–2023 | Self | Self - Guest |
| IMDb Interviews | 2023 | Self | Self |
| Hollywood First Look | 2023 | Self | Self |
| Project Greenlight: A New Generation | 2023 | Self | Self |
| The Project | 2023 | Self | Self - Actor |
| Fantastic | 2023 | Self | Self - Guest |
| The Kelly Clarkson Show | 2023 | Self | Self - Guest |
| The Jennifer Hudson Show | 2023 | Self | Self - Guest |
| Let's Shoot! with Pete Chatmon TV Series | 2020–2023 | Self | Self |
| 54th NAACP Image Awards | 2023 | Self | Self - Presenter |
| The Real Friends of WeHo | 2023 | Self | Self |
| The Daily Show | 2017–2022 | Self | Self |
| Archetypes | 2022 | Self | Self - Guest |
| The Hair Tales | 2022 | Self | Self |
| The 74th Primetime Emmy Awards | 2022 | Self | Self - Nominee |
| Late Night with Seth Meyers | 2019–2022 | Self | Self - Guest |
| Extra | 2018–2022 | Self | Self |
| Legendary | 2022 | Self | Self - Guest Judge |
| The 27th Annual Critics' Choice Awards | 2022 | Self | Self - Presenter |
| 53rd NAACP Image Awards | 2022 | Self | Self - Presenter & Winner |
| The Envelope Podcast Series | 2021 | Self | Self - Guest |
| As Heard on Insecure Video | 2021 | Self | Self |
| CBS Mornings | 2021 | Self | Self - Guest |
| The Late Show with Stephen Colbert | 2017–2021 | Self | Self - Guest |
| Tamron Hall | 2021 | Self | Self |
| Hollywood Insider | 2020–2021 | Self | Self |
| BET Awards 2021 | 2021 | Self | Self - Presenter |
| Desus & Mero | 2019–2021 | Self | Self |
| Jemele Hill Is Unbothered | 2021 | Self | Self - Guest |
| 52nd NAACP Image Awards | 2021 | Self | Self - Winner |
| Finding Your Roots with Henry Louis Gates, Jr. | 2021 | Self | Self |
| Saturday Night Live | 2020 | Self | Self - Host |
| The 72nd Primetime Emmy Awards | 2020 | Self | Self - Nominee |
| Live with Kelly and Mark | 2020 | Self | Self - Guest |
| Made in Hollywood | 2020 | Self | Self |
| Dish Nation | 2018–2020 | Self | Self |
| AFI Movie Club | 2020 | Self | Self |
| Celebrity Page | 2020 | Self | Self |
| 90 Day Fiancé: Pillow Talk | 2020 | Self | Self |
| GMA3: What You Need to Know | 2020 | Self | Self |
| The 62nd Annual Grammy Awards | 2020 | Self | Self - Presenter |
| 92nd Academy Awards Nominations Announcement TV Special | 2020 | Self | Self |
| 2019 Soul Train Awards: Red Carpet Special TV Special | 2019 | Self | Self |
| Black Girls Rock! | 2019 | Self | Self - Presenter |
| Watch What Happens Live with Andy Cohen | 2019 | Self | Self - Guest |
| Complex x Fuse | 2019 | Self | Self |
| CBS Mornings | 2016–2019 | Self | Self - Guest |
| The IMDb Show | 2019 | Self | Self - Guest |
| 50th NAACP Image Awards | 2019 | Self | Self - Presenter |
| Complex Con(versations) TV Mini Series | 2019 | Self | Self |
| WGN Morning News | 2019 | Self | Self |
| From the Mouths of Babes | 2016–2019 | Self | Self |
| The Real | 2018 | Self | Self |
| Jimmy Kimmel Live! | 2018 | Self | Self - Guest |
| E! Live from the Red Carpet | 2017–2018 | Self | Self |
| The Ellen DeGeneres Show | 2018 | Self | Self - Guest |
| The 70th Primetime Emmy Awards | 2018 | Self | Self - Nominee |
| Hot Ones | 2018 | Self | Self - Guest |
| Variety Studio: Actors on Actors | 2017–2018 | Self | Self |
| Entertainment Tonight Canada | 2018 | Self | Self |
| 2017 Final Draft Awards TV Special | 2018 | Self | Self |
| 49th NAACP Image Awards Red Carpet | 2018 | Self | Self |
| 49th NAACP Image Awards | 2018 | Self | Self |
| 75th Golden Globe Awards | 2018 | Self | Self - Nominee |
| Genius Talks TV Special | 2017 | Self | Self |
| Audi Think Faster TV Series | 2017 | Self | Self |
| The 69th Primetime Emmy Awards | 2017 | Self | Self - Presenter |
| Black Girls Rock! 2017 | 2017 | Self | Self - Honoree |
| Larry King Now | 2017 | Self | Self - Guest |
| The Talk | 2017 | Self | Self - Guest |
| The 2017 ESPY Awards | 2017 | Self | Self |
| Close Up with the Hollywood Reporter | 2017 | Self | Self |
| Essence 10th Anniversary Black Women in Hollywood Awards | 2017 | Self | Self |
| 32nd Film Independent Spirit Awards | 2017 | Self | Self - Presenter |
| ABFF Honors | 2017 | Self | Self |
| The 48th NAACP Image Awards | 2017 | Self | Self - Presenter |
| Last Week | 2017 | Self | Self |
| The 74th Annual Golden Globe Awards 2017 | 2017 | Self | Self - Nominee |
| Conan | 2016 | Self | Self - Guest |
| On Story | 2016 | Self | Self |
| Essence Ninth Annual Black Women in Hollywood | 2016 | Self | Self |
| Issa Rae Presents Fruit Podcast Series | 2016–2017 | Self | Self - Host |
| Get Your Life | 2015 | Self | Self |
| Am I: The Film Short | 2015 | Self | Self |
| Exhale | 2013–2015 | Self | Self - Co-Host |
| The Nightly Show with Larry Wilmore | 2015 | Self | Self - Panelist |
| TakePart Live | 2013 | Self | Self - Guest |
| Inside Web Series | 2013 | Self | Self |
| How Men Become Dogs | 2013 | Self | Self |
| Instacurity | 2013 | Self | Self |
| BAD25: The Short Films of Michael Jackson | 2012 | Self | Self |
| Totally Biased with W. Kamau Bell | 2012 | Self | Self - Guest |
| Dish Nation | 2022–2025 | Archive Footage | Self (archive footage) |
| Entertainment Tonight | 2019–2025 | Archive Footage | Self (archive footage) |
| Access Hollywood | 2024 | Archive Footage | Self (archive footage) |
| The Project | 2024 | Archive Footage | Self - Actor (archive footage) |
| The Beat with Ari Melber | 2023 | Archive Footage | Self (archive footage) |
| See It Loud: The History of Black Television | 2023 | Archive Footage | Self (archive footage) |
| Black Pop: Celebrating the Power of Black Culture | 2023 | Archive Footage | Self (archive footage) |
| History of the Sitcom | 2021 | Archive Footage | Issa Dee (archive footage) |
| Celebrity Page | 2020 | Archive Footage | Self (archive footage) |
| The Ben Shapiro Show | 2017 | Archive Footage | Self (archive footage, uncredited) |