| Jenny Slate: Seasoned Professional | 2024 | Writer | Writer |
| Marcel the Shell with Shoes On | 2021 | Writer | based on characters created by |
| Jenny Slate: Stage Fright | 2019 | Writer | Writer |
| Hospital Head Doctor | 2016 | Writer | Writer |
| Marcel the Shell with Shoes on, Three | 2014 | Writer | written by |
| Catherine | 2014 | Writer | writer |
| Catherine | 2013 | Writer | writer |
| Marcel the Shell with Shoes on, Two | 2011 | Writer | written by |
| Marcel the Shell with Shoes On | 2010 | Writer | written by |
| The Great North | 2021–2025 | Actress | Judy Tobin (voice) |
| Dying for Sex | 2025 | Actress | Nikki Boyer |
| The Electric State | 2025 | Actress | Penny Pal (voice) |
| Bob's Burgers | 2012–2024 | Actress | Tammy |
| It Ends with Us | 2024 | Actress | Allysa |
| Big Mouth | 2017–2023 | Actress | Brittany MacDell |
| Adventure Time: Fionna & Cake | 2023 | Actress | Huntress (voice) |
| Past My Bedtime | 2022 | Actress | |
| The Bob's Burgers Movie | 2022 | Actress | Tammy (voice) |
| Everything Everywhere All at Once | 2022 | Actress | Debbie the Dog Mom |
| Muppet Babies | 2018–2022 | Actress | Ms. Nanny |
| I Want You Back | 2022 | Actress | Emma |
| Marcel the Shell with Shoes On | 2021 | Actress | Marcel (voice) |
| Q-Force | 2021 | Actress | (voice) |
| On the Rocks | 2020 | Actress | Vanessa |
| Elena of Avalor | 2020 | Actress | Cahu (voice) |
| Super Gidget | 2019 | Actress | Gidget (voice) |
| Earth Break Podcast Series | 2019 | Actress | Lynn Gellert (voice) |
| The Secret Life of Pets 2 | 2019 | Actress | Gidget (voice) |
| The Unauthorized Bash Brothers Experience | 2019 | Actress | Stacy |
| Star vs. the Forces of Evil | 2015–2019 | Actress | Ponyhead |
| The Simpsons | 2019 | Actress | Piper Paisley (voice) |
| The Sunlit Night | 2019 | Actress | Frances |
| Venom | 2018 | Actress | Dr. Dora Skirth |
| Clarence | 2018 | Actress | Pipi |
| Hotel Artemis | 2018 | Actress | Morgan |
| Adventure Time | 2016–2017 | Actress | Huntress Wizard (voice) |
| Lady Dynamite | 2016–2017 | Actress | Karen Grisham Life Coach |
| Star v the Forces of Evil: 360° Interdimensional Scavenger Hunt | 2017 | Actress | Ponyhead (voice) |
| Comrade Detective | 2017 | Actress | Jane (voice) |
| Despicable Me 3 | 2017 | Actress | Valerie Da Vinci (voice) |
| Batman Is Just Not That Into You | 2017 | Actress | Harley Quinn (voice) |
| Aardvark | 2017 | Actress | Emily Milburton |
| Gifted | 2017 | Actress | Bonnie |
| The Lego Batman Movie | 2017 | Actress | Harley Quinn (voice) |
| The Polka King | 2017 | Actress | Marla Lewan |
| Landline | 2017 | Actress | Dana |
| Brain on Fire | 2016 | Actress | Margo |
| Zoolander: Super Model | 2016 | Actress | Nani (voice) |
| The Secret Life of Pets | 2016 | Actress | Gidget (voice) |
| Girls | 2012–2016 | Actress | Tally Schifrin |
| Animals. | 2016 | Actress | Snake (voice) |
| My Blind Brother | 2016 | Actress | Rose |
| Zootopia | 2016 | Actress | Bellwether (voice) |
| Joshy | 2016 | Actress | Jodi |
| The Holiday Greeting | 2015 | Actress | Gidget (voice) |
| Stray Day TV Mini Series | 2015–2016 | Actress | |
| Married | 2014–2015 | Actress | Jess |
| Kroll Show | 2013–2015 | Actress | Liz B. |
| Parks and Recreation | 2013–2015 | Actress | Mona-Lisa Saperstein |
| Digging for Fire | 2015 | Actress | Yoga Couple |
| House of Lies | 2013–2015 | Actress | Sarah Guggenheim |
| 9 Kisses | 2014 | Actress | Woman in Chariot #1 |
| Marcel the Shell with Shoes on, Three | 2014 | Actress | Marcel (voice) |
| Brooklyn Nine-Nine | 2014 | Actress | Bianca |
| The Longest Week | 2014 | Actress | Jocelyn #1 |
| Catherine | 2014 | Actress | Catherine |
| Obvious Child | 2014 | Actress | Donna |
| Comedy Bang Bang: The Podcast | 2014 | Actress | Pretty Liz |
| Crush | 2013 | Actress | Friend |
| Super Fun Night | 2013 | Actress | Helen-Alice |
| Hello Ladies | 2013 | Actress | Amelia Gordon |
| Bitch | 2013 | Actress | Molly Horner |
| Catherine | 2013 | Actress | Catherine |
| Raising Hope | 2012 | Actress | Joan |
| The Lorax | 2012 | Actress | Ted's Mom (voice) |
| This Means War | 2012 | Actress | Emily |
| Alvin and the Chipmunks: Chipwrecked | 2011 | Actress | Zoe |
| Marcel the Shell with Shoes on, Two | 2011 | Actress | Marcel (voice) |
| Ugly Americans | 2011 | Actress | Jaclyn (voice) |
| Bored to Death | 2009–2010 | Actress | Stella |
| Marcel the Shell with Shoes On | 2010 | Actress | Marcel (voice) |
| Saturday Night Live | 2009–2010 | Actress | Various |
| Obvious Child | 2009 | Actress | Donna |
| Brothers | 2009 | Actress | Annette |
| The Lonely Island: Threw It on the Ground | 2009 | Actress | Girlfriend (uncredited) |
| Late Night with Jimmy Fallon | 2009 | Actress | Jenny the Page (uncredited) |
| Important Things with Demetri Martin | 2009 | Actress | Bride |
| The Whitest Kids U'Know | 2008 | Actress | Trevor's Date |
| Honesty | 2007 | Actress | Girl |
| Starved | 2005 | Actress | Member of Belt Tighteners (uncredited) |
| Jenny Slate: Seasoned Professional | 2024 | Producer | executive producer |
| Marcel the Shell with Shoes On | 2021 | Producer | producer |
| Jenny Slate: Stage Fright | 2019 | Producer | executive producer |
| The Sunlit Night | 2019 | Producer | producer |
| Landline | 2017 | Producer | executive producer |
| Obvious Child | 2014 | Producer | executive producer |
| I Want You Back | 2022 | Soundtrack | performer: "Torn", "You Oughta Know", "Suddenly Seymour" |
| Big Mouth | 2017–2021 | Soundtrack | performer: "You'll Always Have Shame" |
| Marcel the Shell with Shoes On | 2021 | Soundtrack | performer: "Linger", "Move it, Groove it", "Peaceful, Easy Feeling" |
| Bob's Burgers | 2014–2016 | Soundtrack | performer: "Ave Maria", "We're Going to Dinner" |
| Marcel the Shell with Shoes on, Three | 2014 | Soundtrack | performer: "A Perfect Day" (uncredited) |
| Saturday Night Live | 2009–2010 | Soundtrack | performer: "What Up With That" |
| The Kelly Clarkson Show | 2022–2025 | Self | Self |
| Today | 2014–2025 | Self | Self - Guest |
| Entertainment Tonight | 2014–2025 | Self | Self |
| The Late Show with Stephen Colbert | 2016–2025 | Self | Self |
| The View | 2025 | Self | Self |
| Good Morning America | 2024–2025 | Self | Self - Guest |
| Fresh Air | 2024 | Self | Self - Guest |
| The Drew Barrymore Show | 2020–2024 | Self | Self - Guest |
| Late Night with Seth Meyers | 2014–2024 | Self | Self - Guest |
| ABC News Breakfast | 2024 | Self | Self - Actress |
| The Project | 2024 | Self | Self - Actor |
| Off Script with the Hollywood Reporter | 2024 | Self | Self - Guest |
| In Creative Company | 2023–2024 | Self | Self |
| Jenny Slate: Seasoned Professional | 2024 | Self | Self |
| Jimmy Kimmel Live! | 2014–2024 | Self | Self - Guest |
| The 29th Annual Critics' Choice Awards | 2024 | Self | Self - Presenter |
| Elmo's Mindfulness Spectacular! Video | 2023 | Self | Self |
| How Did This Get Made? | 2017–2023 | Self | Self - Guest |
| The Oscars | 2023 | Self | Self - Audience Member |
| 75th Writers Guild of America Awards TV Special | 2023 | Self | Self - Presenter |
| 38th Film Independent Spirit Awards | 2023 | Self | Self - Presenter |
| CBS Mornings | 2023 | Self | Self |
| The 29th Annual Screen Actors Guild Awards | 2023 | Self | Self - Presenter & Winner |
| The 6th Annual HCA Film Awards TV Special | 2023 | Self | Self |
| The Empire Film Podcast | 2023 | Self | Self |
| The Late Late Show with James Corden | 2016–2023 | Self | Self - Guest |
| The 28th Annual Critics' Choice Awards | 2023 | Self | Self |
| 80th Golden Globe Awards | 2023 | Self | Self - Audience Member |
| Archetypes | 2022 | Self | Self - Guest |
| Katie's Crib Podcast Series | 2022 | Self | Self - Guest |
| Live with Kelly and Mark | 2017–2022 | Self | Self - Guest |
| The Daily Show: Ears Edition | 2022 | Self | Self |
| The Daily Show | 2019–2022 | Self | Self - Guest |
| Talk Easy with Sam Fragoso | 2017–2022 | Self | Self |
| Good Mythical Morning | 2022 | Self | Self |
| SmartLess | 2022 | Self | Self - Guest |
| CBS News Sunday Morning with Jane Pauley | 2022 | Self | Self - Guest |
| Life is Short with Justin Long | 2022 | Self | Self - Guest |
| Made in Hollywood | 2017–2022 | Self | Self |
| Hollywood First Look | 2022 | Self | Self |
| The Tonight Show Starring Jimmy Fallon | 2014–2022 | Self | Self - Guest |
| Hollywood Insider | 2020–2021 | Self | Self |
| Late Night with Seth Meyers Podcast | 2020 | Self | Self - Guest |
| Earth to Ned | 2020 | Self | Self - Guest Star |
| Introducing 'Tell Me: Women Filmmakers, Women's Stories' Short | 2020 | Self | Self |
| Big Mouth Live Table Read TV Special | 2020 | Self | Self |
| A Little Late with Lilly Singh | 2019 | Self | Self |
| Conan | 2012–2019 | Self | Self - Guest |
| Jenny Slate: Stage Fright | 2019 | Self | Self |
| Celebrity Page | 2017–2019 | Self | Self |
| THR Studio at Park City TV Mini Series | 2019 | Self | Self |
| Deadline Studio | 2019 | Self | Self |
| Front Row Flynn | 2019 | Self | Self |
| Venom: The Anti-Hero | 2018 | Self | Self |
| Venom: From Symbiote to Screen | 2018 | Self | Self |
| IMDb Interviews | 2018 | Self | Self - Guest |
| The Making of Aardvark Short | 2017 | Self | Self |
| Tavis Smiley | 2017 | Self | Self - Guest |
| Extra | 2017 | Self | Self |
| Off Camera with Sam Jones | 2017 | Self | Self |
| 32nd Film Independent Spirit Awards | 2017 | Self | Self - Presenter |
| Variety Studio | 2017 | Self | Self |
| Drunk History | 2013–2016 | Self | Self - Narrator |
| Unqualified | 2016 | Self | Self - Guest |
| 30th Annual Film Independent Spirit Awards | 2015 | Self | Self - Nominee & Presenter |
| 20th Annual Critics' Choice Movie Awards | 2015 | Self | Self |
| Variety Studio: Actors on Actors | 2014 | Self | Self |
| WTF with Marc Maron | 2014 | Self | Self - Guest |
| Dan Klein: This Is Comedy | 2014 | Self | Self |
| The Getaway | 2014 | Self | Self |
| The Ellen DeGeneres Show | 2014 | Self | Self - Guest |
| Late Show with David Letterman | 2014 | Self | Self - Guest |
| The Meltdown with Jonah and Kumail | 2014 | Self | Self - Guest |
| HuffPost Live Conversations | 2014 | Self | Self |
| 2014 MuchMusic Video Awards | 2014 | Self | Self |
| Fashion Police | 2014 | Self | Self - Guest |
| Chelsea Lately | 2014 | Self | Self - Guest |
| Kevin Pollak's Chat Show | 2014 | Self | Self - Guest |
| Kroll Show | 2013–2014 | Self | Self |
| The Pete Holmes Show | 2014 | Self | Self - Guest |
| Live@Sundance TV Series | 2014 | Self | Self |
| @midnight | 2014 | Self | Self |
| Getting Doug with High | 2013 | Self | Self |
| The Evening Hour with Sean Conroy TV Series | 2013 | Self | Self |
| Love You, Mean It with Whitney Cummings | 2012 | Self | Self |
| Literary Death Match Video | 2012 | Self | Self - Reader |
| Smile | 2012 | Self | Self |
| Rock Center with Brian Williams | 2011 | Self | Self |
| AM Northwest | 2011 | Self | Self |
| The Electric Company | 2011 | Self | Self |
| Top 40 Videos of 2008 TV Movie | 2008 | Self | Self |
| 100 Greatest Songs of the 90s | 2007 | Self | Self |
| Scott Bateman Presents Scott Bateman Presents | 2007 | Self | Self (voice) |
| In Dispute: Lively v Baldoni | 2025 | Archive Footage | Self (archive footage) |
| He Said, She Said: Blake Lively vs Justin Baldoni | 2025 | Archive Footage | Self (archive footage) |
| Entertainment Tonight | 2014–2025 | Archive Footage | Self (archive footage) |
| Celebrity Page | 2018–2019 | Archive Footage | Self (archive footage) |
| Welcome to the Basement | 2015 | Archive Footage | Donna Stern (archive footage) |
| SNL Sports Spectacular | 2014 | Archive Footage | Pippa (archive footage, uncredited) |
| Saturday Night Live: Halloween | 2013 | Archive Footage | Various (archive footage, uncredited) |
| Saturday Night Live Backstage | 2011 | Archive Footage | Various (archive footage) |
| The Women of SNL | 2010 | Archive Footage | Gretchen (archive footage) |
| Saturday Night Live Presents: Sports All-Stars | 2010 | Archive Footage | Singer (archive footage, uncredited) |