| Harriet the Spy | 2023 | Actress | Dr. Wagner (voice) |
| Unicorn Boy | 2023 | Actress | Violet (voice) |
| Gossip Girl | 2022–2023 | Actress | Georgina Sparks (as Michelle Tractenberg) |
| Human Kind Of | 2018 | Actress | Judy Reilly (voice) |
| Robot Chicken | 2006–2018 | Actress | Harriet the Spy |
| Sister Cities | 2016 | Actress | Dallas Baxter |
| The Christmas Gift | 2015 | Actress | Megan Phillips |
| SuperMansion | 2015 | Actress | Blood Moon (voice) |
| Guidance | 2015 | Actress | Anna |
| Sleepy Hollow | 2015 | Actress | Abigail Adams |
| Save the Date | 2014 | Actress | Hillary |
| The Scribbler | 2014 | Actress | Alice |
| NCIS: Los Angeles | 2013 | Actress | Lily Lockhart |
| Killing Kennedy | 2013 | Actress | Marina Oswald |
| Sexy Evil Genius | 2013 | Actress | Miranda Prague |
| Criminal Minds | 2013 | Actress | Diane Turner |
| Gossip Girl | 2008–2012 | Actress | Georgina Sparks |
| Untitled Peter Knight Comedy Project | 2011 | Actress | Gracie |
| Weeds | 2011 | Actress | Emma Karlin |
| Love Bites | 2011 | Actress | Jodie |
| Take Me Home Tonight | 2011 | Actress | Ashley |
| Zac Posen: Z Spoke Spring/Summer 2011 Collection | 2010 | Actress | |
| Mercy | 2009–2010 | Actress | Nurse Chloe Payne |
| Superman/Shazam!: The Return of Black Adam | 2010 | Actress | Bar Girl (voice) |
| DC Showcase Original Shorts Collection | 2010 | Actress | Bar Girl (segment "Jonah Hex") (voice) |
| DC Showcase: Jonah Hex | 2010 | Actress | Bar Girl (voice) |
| Cop Out | 2010 | Actress | Ava |
| The Super Hero Squad Show | 2009 | Actress | Valkyrie (voice) |
| 17 Again | 2009 | Actress | Maggie |
| Against the Current | 2009 | Actress | Suzanne |
| Kohl's: Candies Commercial Video | 2008 | Actress | Michelle Trachtenberg |
| The Circuit | 2008 | Actress | Kylie Shines |
| Dragonlance: Dragons of Autumn Twilight | 2008 | Actress | Tika (voice) |
| Fall Out Boy: This Ain't a Scene, It's an Arms Race | 2007 | Actress | Guest at funeral (uncredited) |
| The Hill | 2007 | Actress | Maggie Rogers |
| Kickin' It Old Skool: Deleted Scenes | 2007 | Actress | Girl |
| Black Christmas | 2006 | Actress | Melissa |
| Law & Order: Criminal Intent | 2006 | Actress | Lisa Willow Tyler |
| Beautiful Ohio | 2006 | Actress | Sandra |
| House | 2006 | Actress | Melinda Bardach |
| The Dive from Clausen's Pier | 2005 | Actress | Carrie Beal |
| Ice Princess | 2005 | Actress | Casey Carlyle |
| Mysterious Skin | 2004 | Actress | Wendy |
| Six Feet Under | 2004 | Actress | Celeste |
| EuroTrip | 2004 | Actress | Jenny |
| Trapt: Echo | 2004 | Actress | Girlfriend |
| Buffy the Vampire Slayer | 2000–2003 | Actress | Dawn Summers |
| A Father's Choice | 2000 | Actress | Kelly McClain |
| Can't Be Heaven | 1999 | Actress | Julie |
| Bonne Nuit | 1999 | Actress | Emma Reeves |
| Inspector Gadget | 1999 | Actress | Penny |
| Richie Rich's Christmas Wish | 1998 | Actress | Gloria |
| Guys Like Us | 1998 | Actress | Katie |
| Meego | 1997 | Actress | Maggie Parker |
| Harriet the Spy: How to Be a Spy Tip - Gloves | 1996 | Actress | Harriet M. Welsch |
| A Holiday for Love | 1996 | Actress | Noelle Murphy |
| Space Cases | 1996 | Actress | Prankster #1 |
| Dave's World | 1996 | Actress | Angela |
| Harriet the Spy | 1996 | Actress | Harriet M. Welsch |
| The Adventures of Pete & Pete | 1994–1996 | Actress | Nona Mecklenberg |
| Secret Sins | 1995 | Actress | Lena (uncredited) |
| All My Children | 1994 | Actress | Lily |
| Clarissa Explains It All | 1993 | Actress | Elsie Soaperstein |
| Law & Order | 1991 | Actress | Dinah Driscoll (uncredited) |
| Meet, Marry, Murder Hosted by Michelle Trachtenberg | 2021 | Producer | executive producer |
| Guidance | 2016–2017 | Producer | executive producer |
| Gossip Girl: XO XO | 2012 | Thanks | special thanks |
| Kickin' It Old Skool | 2007 | Thanks | very special thanks |
| Blue's Clues | 1998 | Thanks | special thanks |
| Buffy the Vampire Slayer | 2001 | Soundtrack | performer: "Dawn's Lament", "What You Feel", "Where Do We Go From Here?" |
| Spyral | 2024 | Self | Michelle Cody White (voice) |
| Meet, Marry, Murder Hosted by Michelle Trachtenberg | 2021 | Self | Self - Host |
| Celebrity Wheel of Fortune | 2021 | Self | Self - Celebrity Contestant |
| Celebrity Page | 2021 | Self | Self |
| Entertainment Tonight | 2008–2021 | Self | Self |
| Daily Blast Live | 2021 | Self | Self |
| Showbiz Junkies TV Series | 2021 | Self | Self |
| Maximo TV Red Carpet Arrivals | 2012–2019 | Self | Self |
| EW Reunites | 2017 | Self | Self |
| Chopped Junior | 2016 | Self | Self - Judge |
| Last Week Tonight with John Oliver | 2016 | Self | (voice) |
| Hollywood Game Night | 2014–2015 | Self | Self - Celebrity Player |
| StompOutBullying: with Michelle Trachtenberg | 2013 | Self | Self |
| Big Morning Buzz Live | 2013 | Self | Self |
| The Arsenio Hall Show | 2013 | Self | Self - Guest |
| Kathy | 2013 | Self | Self - Guest |
| Gossip Girl: Series Retrospective | 2012 | Self | Self |
| Gossip Girl: XO XO | 2012 | Self | Self |
| Watch What Happens Live with Andy Cohen | 2012 | Self | Self - Guest |
| Global Citizen Festival TV Special | 2012 | Self | Self |
| E! Investigates TV Series | 2012 | Self | Self |
| Rick Santorum Aborts Presidential Campaign | 2012 | Self | Self |
| The 2011 Independent Spirit Awards | 2011 | Self | Self |
| The Seven | 2011 | Self | Self |
| The 68th Annual Golden Globe Awards | 2011 | Self | Self |
| The City | 2010 | Self | Self (uncredited) |
| Teenage Paparazzo | 2010 | Self | Self (uncredited) |
| Talk Stoop | 2010 | Self | Self - Guest |
| Rachael Ray | 2010 | Self | Self - Guest |
| Zac Goes Back Video | 2009 | Self | Self |
| Going Back to 17 | 2009 | Self | Self |
| Macy's Thanksgiving Day Parade | 2009 | Self | Self |
| NYC Prep | 2009 | Self | Self |
| Late Night with Jimmy Fallon | 2009 | Self | Self - Guest |
| The Bonnie Hunt Show | 2009 | Self | Self - Guest |
| The Hills | 2008 | Self | Self (uncredited) |
| Hotel Gramercy Park | 2008 | Self | Self |
| May All Your Christmases Be Black | 2007 | Self | Self |
| Space Top 10 Countdown | 2007 | Self | Self |
| The 64th Annual Golden Globe Awards | 2007 | Self | Self |
| Fuse Celebrity Playlist | 2006 | Self | Self - Guest |
| Late Night with Conan O'Brien | 2006 | Self | Self - Guest |
| What Have You Done?: The Remaking of 'Black Christmas' | 2006 | Self | Self |
| E! True Hollywood Story | 2006 | Self | Self |
| Punk'd | 2006 | Self | Self |
| Biography | 2003–2005 | Self | Self |
| Jimmy Kimmel Live! | 2005 | Self | Self - Guest |
| Total Request Live | 2005 | Self | Self |
| The View | 2005 | Self | Self - Guest |
| The 20th IFP Independent Spirit Awards | 2005 | Self | Self - Performer (segment "Primer") |
| 'Buffy': Season 7 Overview | 2004 | Self | Self |
| Buffy the Vampire Slayer: Dawn | 2004 | Self | Self |
| 2004 Much Music Video Music Awards | 2004 | Self | Self |
| 2004 MTV Movie Awards | 2004 | Self | Self - Audience Member (uncredited) |
| Eurotrip: The Making of 'Eurotrip' | 2004 | Self | Self |
| Eurotrip: Nude Beach Exposed | 2004 | Self | Self |
| 'Buffy': Season 6 Overview | 2004 | Self | Self |
| Best Week Ever with Paul F. Tompkins | 2004 | Self | Self |
| Buffy Wraps | 2004 | Self | Self |
| The Late Late Show with Craig Kilborn | 2004 | Self | Self - Guest |
| On-Air with Ryan Seacrest | 2004 | Self | Self - Guest |
| MTV Hits | 2004 | Self | Self |
| The Sharon Osbourne Show | 2004 | Self | Self - Guest |
| Truth or Scare | 2001–2003 | Self | Self - Host |
| Behind the Scenes of 'Buffy the Vampire Slayer' Video | 2003 | Self | Self |
| Buffy Goes to Work Video | 2003 | Self | Self |
| Buffy the Vampire Slayer: Behind the Scenes of 'Once More with Feeling' | 2003 | Self | Self (uncredited) |
| The 60th Annual Golden Globe Awards | 2003 | Self | Self |
| HypaSpace | 2002 | Self | Self |
| The Teen Choice Awards 2002 | 2002 | Self | Self - Presenter |
| Buffy's Back - The E! Original Special | 2001 | Self | Self |
| 70th Annual Hollywood Christmas Parade TV Special | 2001 | Self | Self |
| Mad TV | 2000–2001 | Self | Self - Special Guest |
| The Teen Choice Awards 2001 | 2001 | Self | Self |
| The Rosie O'Donnell Show | 1996–2001 | Self | Self - Guest |
| The Tonight Show with Jay Leno | 1999 | Self | Self - Guest |
| Nickelodeon Kids' Choice Awards '99 | 1999 | Self | Self |
| Blue's Birthday | 1998 | Self | Self |
| Reading Rainbow | 1998 | Self | Self (voice) |
| Blue's Clues | 1998 | Self | Self |
| The 1998 Annual Kid's Choice Awards | 1998 | Self | Self |
| Figure It Out | 1997–2013 | Self | Self |
| Burger King: with Michelle Trachtenberg | 1991 | Self | Girl |
| Entertainment Tonight | 2024–2025 | Archive Footage | Self (archive footage) |
| Sidewalks Entertainment | 2025 | Archive Footage | Self - Guest (archive footage) |
| Good Morning America | 2025 | Archive Footage | Self (archive footage) |
| Inside Edition | 2025 | Archive Footage | Self (archive footage) |
| ABC News Breakfast | 2025 | Archive Footage | Self - Actress (archive footage) |
| Access Hollywood | 2025 | Archive Footage | Self (archive footage) |
| Criminal Minds | 2020 | Archive Footage | Diane Turner (archive footage, uncredited) |
| Black Christmas: Deleted Scenes Video | 2006 | Archive Footage | Melissa Kitt (archive footage) |
| EuroTrip: Deleted Scenes | 2004 | Archive Footage | Jenny (archive footage) |