| Family Guy | 1999–2025 | Actress | Meg Griffin |
| Goodrich | 2024 | Actress | Grace |
| That '90s Show | 2023 | Actress | Jackie Burkhart |
| Stoner Cats | 2021–2022 | Actress | Fefe |
| Luckiest Girl Alive | 2022 | Actress | Ani Fanelli |
| The Boys | 2022 | Actress | Mila Kunis (uncredited) |
| Warped Kart Racers | 2022 | Actress | Meg Griffin (voice) |
| Talk'n Shop | 2021 | Actress | Mila Kunis |
| Breaking News in Yuba County | 2021 | Actress | Nancy |
| Ariana Grande & Justin Bieber: Stuck with U | 2020 | Actress | Mila Kunis |
| Curb Your Enthusiasm | 2020 | Actress | Mila Kunis |
| Four Good Days | 2020 | Actress | Molly |
| Wonder Park | 2019 | Actress | Greta (voice) |
| The Spy Who Dumped Me | 2018 | Actress | Audrey |
| A Bad Moms Christmas | 2017 | Actress | Amy |
| Bad Moms | 2016 | Actress | Amy |
| Hell and Back | 2015 | Actress | Deema (voice) |
| Jupiter Ascending | 2015 | Actress | Jupiter Jones |
| Annie | 2014 | Actress | Andrea Alvin |
| The Angriest Man in Brooklyn | 2014 | Actress | Dr. Sharon Gill |
| Family Guy: The Quest for Stuff | 2014 | Actress | Meg Griffin (voice) |
| Two and a Half Men | 2014 | Actress | Vivian |
| Third Person | 2013 | Actress | Julia |
| Blood Ties | 2013 | Actress | Natalie |
| Oz the Great and Powerful | 2013 | Actress | Theodora |
| Family Guy: Back to the Multiverse | 2012 | Actress | Meg Griffin (voice) |
| The Color of Time | 2012 | Actress | Catherine |
| Ted | 2012 | Actress | Lori Collins |
| Robot Chicken | 2005–2011 | Actress | Belle |
| Friends with Benefits | 2011 | Actress | Jamie |
| Black Swan | 2010 | Actress | Lily |
| Date Night | 2010 | Actress | Whippit |
| The Late Late Show with Craig Ferguson | 2010 | Actress | Snooki |
| The Book of Eli | 2010 | Actress | Solara |
| Mams Taylor: L.A. Girls | 2009 | Actress | Mila Kunis |
| Tom Cool | 2009 | Actress | Little Boy Matson |
| The Cleveland Show | 2009 | Actress | Meg Griffin (voice) |
| Extract | 2009 | Actress | Cindy |
| Max Payne | 2008 | Actress | Mona Sax |
| Boot Camp | 2008 | Actress | Sophie |
| Forgetting Sarah Marshall | 2008 | Actress | Rachel Jansen |
| The Hills with James Franco and Mila Kunis | 2007 | Actress | Audrina |
| Family Guy 100th Episode Special | 2007 | Actress | Meg Griffin (voice) |
| Moving McAllister | 2007 | Actress | Michelle McAllister |
| After Sex | 2007 | Actress | Nikki |
| Family Guy Video Game! | 2006 | Actress | Meg Griffin (voice) |
| Saints Row | 2006 | Actress | Tanya Winters (voice) |
| That '70s Show | 1998–2006 | Actress | Jackie Burkhart |
| That '70s Show Special: The Final Goodbye | 2006 | Actress | Jackie Burkhart |
| Stewie Griffin: The Untold Story | 2005 | Actress | Meg Griffin |
| The Zula Patrol | 2005 | Actress | Charon (voice) |
| The Strokes: The End Has No End | 2004 | Actress | Woman |
| Grounded for Life | 2004 | Actress | Lana |
| The Latin Lover | 2004 | Actress | Girl on street |
| Tony & Tina's Wedding | 2004 | Actress | Tina |
| Mad TV | 2002 | Actress | Daisy |
| American Psycho II: All American Girl | 2002 | Actress | Rachael Newman |
| Get Over It | 2001 | Actress | Basin |
| Aerosmith: Jaded | 2001 | Actress | Jaded Girl |
| Get Real | 2000 | Actress | Taylor Vaughn |
| Sammy | 2000 | Actress | Lola (voice) |
| Milo | 1998 | Actress | Martice (uncredited) |
| Krippendorf's Tribe | 1998 | Actress | Abbey Tournquist |
| Gia | 1998 | Actress | Gia - Age 11 |
| Pensacola: Wings of Gold | 1998 | Actress | Jessie Kerwood |
| 7th Heaven | 1996–1997 | Actress | Ashley |
| Honey, We Shrunk Ourselves! | 1997 | Actress | Jill |
| Nick Freno: Licensed Teacher | 1996–1997 | Actress | Anna-Maria Del Bono |
| Walker, Texas Ranger | 1997 | Actress | Pepper |
| Mila Kunis in Lisa Frank Commercial Video | 1996 | Actress | Mila Kunis |
| Santa with Muscles | 1996 | Actress | Sarah |
| Unhappily Ever After | 1996 | Actress | Chloe |
| Baywatch | 1994–1995 | Actress | Bonnie |
| Hudson Street | 1995 | Actress | Devon |
| Piranha | 1995 | Actress | Susie Grogan |
| Make a Wish, Molly | 1995 | Actress | Melinda |
| The John Larroquette Show | 1995 | Actress | Lucy Sanchez |
| Days of Our Lives | 1994 | Actress | Young Hope |
| Goodrich | 2024 | Producer | executive producer |
| Stoner Cats | 2021–2022 | Producer | executive producer |
| Luckiest Girl Alive | 2022 | Producer | producer (produced by, p.g.a.) |
| The Gimmicks | 2022 | Producer | executive producer |
| A Bad Moms Christmas | 2017 | Producer | executive producer |
| The Angriest Man in Brooklyn | 2014 | Producer | executive producer |
| Robot Chicken | 2006 | Makeup Department | hair stylist |
| The Blockbuster Buster | 2015 | Thanks | dedicatee |
| Family Guy: 200 Episodes Later | 2012 | Thanks | special thanks: to the cast |
| Method | 2011 | Thanks | very special thanks |
| Black Swan: Metamorphosis | 2011 | Thanks | thanks |
| Family Guy | 2001–2017 | Soundtrack | performer: "I Love Trash" |
| Teen Choice Awards 2010 | 2010 | Soundtrack | performer: "Lucky There's A Family Guy" (uncredited) |
| That '70s Show | 1998–2004 | Soundtrack | performer: "On the Good Ship Lollipop" |
| Made in Hollywood | 2010–2024 | Self | Self |
| Today | 2008–2024 | Self | Self - Guest |
| Jimmy Kimmel Live! | 2003–2024 | Self | Self - Guest |
| Entertainment Tonight | 2013–2024 | Self | Self |
| Esquire: YouTube Channel TV Mini Series | 2024 | Self | Self |
| Seth MacFarlane, Mila Kunis, Seth Green & Alex Borstein Talk 25 Years of Family Guy | 2024 | Self | Self |
| Time100: The Most Influential People 2023 | 2023 | Self | Self |
| The Late Late Show with James Corden | 2015–2023 | Self | Self |
| CNN Heroes: Sharing the Spotlight 2022 TV Special | 2022 | Self | Self |
| Harper's Bazaar: YouTube Channel TV Series | 2022 | Self | Self |
| IMDb Interviews | 2022 | Self | Self |
| The Kelly Clarkson Show | 2022 | Self | Self - Guest |
| Bling Empire | 2022 | Self | Self |
| Conan O'Brien Needs a Friend | 2019–2022 | Self | Self - Friend |
| Sunday Today with Willie Geist | 2018–2022 | Self | Self - Guest |
| Access Hollywood | 2016–2022 | Self | Self |
| CNN Heroes Salutes TV Special | 2022 | Self | Self |
| Zervakis & Opdenhövel. Live. | 2022 | Self | Self |
| The Ellen DeGeneres Show | 2008–2021 | Self | Self - Guest |
| Who's Talking to Chris Wallace | 2022 | Self | Self |
| The Oscars | 2022 | Self | Self - Presenter |
| SXSW Gaming Awards 2022 TV Special | 2022 | Self | Voice |
| Ukraine Special. - Krieg in Europa | 2022 | Self | Self |
| Hot Ones | 2021 | Self | Self - Guest (as CL) |
| Dish Nation | 2018–2021 | Self | Self |
| Comic-Con at Home 2021 TV Series | 2021 | Self | Self |
| Armchair Expert with Dax Shepard | 2018–2021 | Self | Self - Guest |
| Nocking Point Presents: Gametime Wine: Ashton Kutcher & Mila Kunis TV Series | 2021 | Self | Self |
| Live with Kelly and Mark | 2016–2021 | Self | Self - Guest |
| Conan | 2012–2021 | Self | Self - Guest |
| Hollywood Insider | 2020–2021 | Self | Self |
| The Late Show with Stephen Colbert | 2021 | Self | Self - Guest |
| Hollywood First Look | 2021 | Self | Self |
| Extra | 2014–2021 | Self | Self |
| The Tonight Show Starring Jimmy Fallon | 2016–2020 | Self | Self - Guest |
| The IMDb Studio at Sundance | 2020 | Self | Self |
| The 71st Primetime Emmy Awards | 2019 | Self | Meg Griffin (voice) |
| The Spy Who Dumped Me: Off Script Video | 2018 | Self | Self - Actress |
| The Spy Who Dumped Me: Outtakes Video | 2018 | Self | Self - Actress |
| Gary Powell: The Action Behind the Film of 'The Spy Who Dumped Me' Video | 2018 | Self | Self - Actress |
| Covert Operations: The Making of 'The Spy Who Dumped Me' Video | 2018 | Self | Self - Actress |
| Celebrity Page | 2018 | Self | Self |
| WGN Morning News | 2017–2018 | Self | Self |
| WTF with Marc Maron | 2018 | Self | Self - Guest |
| 2018 MTV Movie & TV Awards | 2018 | Self | Self |
| 2018 Billboard Music Awards | 2018 | Self | Self - Presenter |
| Lorraine | 2017 | Self | Self - Guest |
| The Price is Right | 2017 | Self | Self - Guest |
| BuzzFeed Celeb | 2017 | Self | Self |
| The Bachelorette | 2017 | Self | Self - Husband Material Judge |
| My Houzz | 2017 | Self | Self |
| Rotten Tomatoes | 2016 | Self | Self |
| The Talk | 2016 | Self | Self - Guest |
| ScreenSlam | 2015–2016 | Self | Self |
| The Insider | 2016 | Self | Self |
| Red Nose Day | 2016 | Self | Self |
| 2016 Billboard Music Awards | 2016 | Self | Self - Presenter |
| Chopped Junior | 2015 | Self | Self - Judge |
| Film '72 | 2015 | Self | Self - Interviewee |
| Brisant | 2015 | Self | Self |
| The Late Late Show with Craig Ferguson | 2009–2014 | Self | Self - Guest |
| Inside Edition | 2014 | Self | Self |
| Blood Ties: Behind the Scenes Video | 2014 | Self | Self - Actress |
| Blood Ties: Behind the Scenes Video | 2014 | Self | Self - Actress |
| 2014 MTV Movie Awards | 2014 | Self | Self - Presenter & Winner |
| E! News | 2014 | Self | Self |
| 71st Golden Globe Awards | 2014 | Self | Self - Presenter (uncredited) |
| ES.TV HD | 2013 | Self | Self - Guest |
| Vivir de cine | 2013 | Self | Self |
| Evening Urgant | 2013 | Self | Self - Guest |
| E! Special: Oz - The Great and Powerful | 2013 | Self | Self |
| taff | 2013 | Self | Self |
| Ant & Dec's Saturday Night Takeaway | 2013 | Self | Self - Guest |
| The Graham Norton Show | 2013 | Self | Self - Guest |
| Fantastic | 2013 | Self | Self |
| Movie Surfers | 2013 | Self | Self |
| Celebrity Style Story | 2013 | Self | Self |
| Comic Con 2012 Live | 2012 | Self | Self |
| The Tonight Show with Jay Leno | 2012 | Self | Self - Guest |
| Maximo TV Red Carpet Arrivals | 2012 | Self | Self |
| Guys Choice Awards 2012 | 2012 | Self | Self |
| 2012 MTV Movie Awards | 2012 | Self | Self - Presenter |
| FOX 25th Anniversary Special | 2012 | Self | Self |
| The 69th Annual Golden Globe Awards | 2012 | Self | Self - Presenter |
| On Set with FWB | 2011 | Self | Self |
| In a Flash: Choreographing a Mob Video | 2011 | Self | Self |
| Comedy of a Sexomedy | 2011 | Self | Self |
| Sesame Street | 2011 | Self | Self |
| Daybreak | 2011 | Self | Self |
| Janela Indiscreta | 2011 | Self | Self |
| Alan Carr: Chatty Man | 2011 | Self | Self - Guest |
| Late Night with Jimmy Fallon | 2011 | Self | Self - Guest |
| Guys Choice Awards 2011 | 2011 | Self | Self - Winner |
| 2011 MTV Movie Awards | 2011 | Self | Self - Presenter |
| Black Swan: Metamorphosis | 2011 | Self | Self |
| La noche de los Oscar TV Series | 2011 | Self | Self |
| The 83rd Annual Academy Awards | 2011 | Self | Self - Presenter |
| W Magazine TV Series | 2011 | Self | Self |
| 17th Annual Screen Actors Guild Awards | 2011 | Self | Self - Nominee |
| The Project | 2010–2011 | Self | Self |
| The 68th Annual Golden Globe Awards | 2011 | Self | Self - Nominee |
| 16th Annual Critics' Choice Movie Awards | 2011 | Self | Self - Nominee |
| The 37th Annual People's Choice Awards | 2011 | Self | Self - Presenter |
| Variety Screening Series TV Mini Series | 2010 | Self | Self |
| Lopez Tonight | 2010 | Self | Self - Guest |
| Date Night: Disaster Dates Video | 2010 | Self | Self |
| The Book of Eli: Eli's Journey | 2010 | Self | Self |
| Family Guy: The Top 20 Characters | 2010 | Self | Self |
| Up Close with Carrie Keagan | 2008–2010 | Self | Self - Guest |
| Extract: Mike Judge's Secret Recipe | 2009 | Self | Self |
| Seth & Alex's Almost Live Comedy Show | 2009 | Self | Meg Griffin (voice) |
| The Tonight Show with Conan O'Brien | 2009 | Self | Self - Guest |
| Spike's Guys Choice | 2009 | Self | Self (as Mila Kunas) |
| Family Guy: The Story So Far... | 2009 | Self | Self |
| Family Guy: Creating the Chaos | 2009 | Self | Self |
| Picture | 2009 | Self | Self |
| VH1 Rock Honors: The Who | 2008 | Self | Self |
| VH1 Rock Honors | 2008 | Self | Self |
| Total Request Live | 2002–2008 | Self | Self |
| The Daily 10 | 2008 | Self | Self |
| DP/30: Conversations About Movies | 2007 | Self | Self |
| Mad TV | 2007 | Self | Self |
| Last Call with Carson Daly | 2002–2007 | Self | Self - Guest |
| Take Alex to Work Day Video | 2006 | Self | |
| Made in Hollywood: Teen Edition | 2006 | Self | Self |
| The Making of 'Saints Row' Video | 2006 | Self | Self |
| E! True Hollywood Story | 2006 | Self | Self |
| The Reichen Show | 2006 | Self | Self - Guest |
| World Domination: The 'Family Guy' Phenomenon | 2005 | Self | Self |
| Punk'd | 2005 | Self | Self |
| The View | 2005 | Self | Self - Guest Host |
| Late Night with Conan O'Brien | 2004–2005 | Self | Self - Guest |
| E! Hollywood Hold'em | 2005 | Self | Self |
| The Oprah Winfrey Show | 2005 | Self | Self - Guest |
| 2004 World Series | 2004 | Self | Self - Crowd Member |
| That '70s Show Bloopers TV Special | 2004 | Self | Jackie Burkhart |
| Making the Show: 'That '70s Show' | 2003 | Self | Jackie Burkhart |
| The Sharon Osbourne Show | 2003 | Self | Self - Guest |
| The Late Late Show with Craig Kilborn | 2001–2003 | Self | Self - Guest |
| The Michael Essany Show | 2003 | Self | Self - Guest |
| MTV Icon: Aerosmith | 2002 | Self | Self |
| That '70s KISS Show | 2002 | Self | Self |
| Seaside Survivor TV Special | 2002 | Self | Self - Host |
| Young Hollywood Awards TV Special | 2002 | Self | Self |
| The Rosie O'Donnell Show | 2001–2002 | Self | Self - Guest |
| Nickelodeon Kids' Choice Awards '02 | 2002 | Self | Self |
| Late Show with David Letterman | 2002 | Self | Self - Guest |
| The Teen Choice Awards 2001 | 2001 | Self | Self |
| Young Hollywood Awards | 2001 | Self | Self |
| Nickelodeon Kids' Choice Awards | 2001 | Self | Self |
| Hollywood Squares | 2000 | Self | Self - Panelist |
| The Teen Choice Awards 2000 | 2000 | Self | Self |
| The 1999 Billboard Music Awards | 1999 | Self | Self |
| The Teen Choice Awards 1999 | 1999 | Self | Self |
| American Manhunt: Osama bin Laden | 2025 | Archive Footage | Self (archive footage) |
| Entertainment Tonight | 2014–2025 | Archive Footage | Self (archive footage) |
| ABC News Breakfast | 2024 | Archive Footage | Self - Actor |
| Worst of Woke Awards 2024 | 2024 | Archive Footage | Self - Nominee (archive footage) |
| Top 5 Hollywood DISASTERS of Summer 2023! Disney and Netflix Lose! Video | 2023 | Archive Footage | Self (archive footage) |
| Tyrone Magnus | 2023 | Archive Footage | Self (archive footage) |
| Nerdrotic | 2023 | Archive Footage | Self (archive footage) |
| Normal World | 2023 | Archive Footage | Self (archive footage) |
| Symone | 2023 | Archive Footage | Self (archive footage) |
| Inside Edition Weekend | 2023 | Archive Footage | Self (archive footage) |
| Inside Edition | 2014–2023 | Archive Footage | Self (archive footage) |
| Extra | 2014–2023 | Archive Footage | Self (archive footage) |
| The Price Is Right 50th Anniversary Special | 2022 | Archive Footage | Self - Special Guest (archive footage) |
| Live with Kelly and Mark | 2022 | Archive Footage | Self (archive footage) |
| Morning Express with Robin Meade | 2022 | Archive Footage | Self (archive footage) |
| Movie Night Extravaganza | 2022 | Archive Footage | Self (archive footage) |
| Kidz Klub! | 2022 | Archive Footage | (archive footage) |
| Celebrity Page | 2017–2020 | Archive Footage | Self (archive footage) |
| Page Six TV | 2019 | Archive Footage | Self (archive footage) |
| First Viewing | 2019 | Archive Footage | Self (archive footage) |
| The Spy Who Dumped Me: Makin' Friends with Hasan Minhaj Video | 2018 | Archive Footage | Self - Actress (archive footage) |
| The Tonight Show Starring Jimmy Fallon | 2018 | Archive Footage | Self (archive footage) |
| Access Hollywood | 2016–2018 | Archive Footage | Self (archive footage) |
| Hoy nos toca | 2017 | Archive Footage | Self - A Bad Moms Christmas |
| The Insider | 2014–2017 | Archive Footage | Self (archive footage) |
| Balls of Glory | 2015 | Archive Footage | Meg Griffin (archive footage) |
| The Drunken Peasants | 2015 | Archive Footage | Self (archive footage) |
| TMZ on TV | 2014 | Archive Footage | Self (archive footage) |
| Red! - Stars, Lifestyle & More | 2013 | Archive Footage | Self (archive footage) |
| taff | 2013 | Archive Footage | Self (archive footage) |
| Flirting with Danger | 2012 | Archive Footage | Self - Friends with Benefits (archive footage) |
| Family Guy: 200 Episodes Later | 2012 | Archive Footage | Meg Griffin (archive footage, uncredited) |
| Chelsea Lately | 2012 | Archive Footage | Self (archive footage) |
| That '70s Show: Holiday Edition | 2011 | Archive Footage | Jackie Burkhart (archive footage) |
| Family Guy: Ground Breaking Gags | 2011 | Archive Footage | Meg Griffin (archive footage, uncredited) |
| 20/20 | 2009 | Archive Footage | Self (archive footage) |
| 50 Most Wicked Women of Primetime | 2004 | Archive Footage | Jackie Burkhart (archive footage) |
| Family Guy: Another Freakin' Mobile Game | 2017 | Archive Sound | Meg Griffin (archive footage) |
| Family Guy: Happy Freakin' Christmas Video | 2006 | Archive Sound | Meg Griffin (archive footage) |