| XX | 2017 | Director | Director (segment "The Birthday Cake", as Annie Clark, directed by) |
| The Nowhere Inn | 2020 | Writer | written by (as Annie Clark) |
| XX | 2017 | Writer | written by (segment "The Birthday Party", as Annie Clark) |
| St. Vincent: Cruel | 2011 | Writer | Writer |
| St. Vincent: Down | 2021 | Actress | St. Vincent |
| St. Vincent: Daddy's Home Music Video | 2021 | Actress | St. Vincent |
| St. Vincent: Pay Your Way in Pain | 2021 | Actress | St. Vincent |
| The Nowhere Inn | 2020 | Actress | Annie Clark (as Annie Clark) |
| St. Vincent: Los Ageless Music Video | 2017 | Actress | St. Vincent |
| St. Vincent: New York | 2017 | Actress | St. Vincent |
| Portlandia | 2012–2014 | Actress | Cuneiform Lead |
| St. Vincent: Digital Witness | 2014 | Actress | St. Vincent |
| St. Vincent: Cheerleader Music Video | 2012 | Actress | St. Vincent |
| St. Vincent: Cruel | 2011 | Actress | St. Vincent |
| St. Vincent: Marrow Music Video | 2009 | Actress | St. Vincent |
| The Nowhere Inn | 2020 | Producer | producer (as Annie Clark, produced by) |
| Olivia Rodrigo: Obsessed | 2024 | Composer | Composer |
| St. Vincent: Down | 2021 | Composer | Composer |
| Olivia Rodrigo: SOUR Prom | 2021 | Composer | Composer (uncredited) |
| Olivia Rodrigo: deja vu (Live Performance) | 2021 | Composer | Composer |
| Olivia Rodrigo: deja vu | 2021 | Composer | Composer |
| The Nowhere Inn | 2020 | Composer | Composer (music by) |
| St. Vincent: Los Ageless Music Video | 2017 | Composer | Composer |
| St. Vincent: New York | 2017 | Composer | Composer |
| XX | 2017 | Composer | Composer (segment "The Birthday Party", as Annie Clark, with music by) |
| Come Swim | 2017 | Composer | Composer |
| David Byrne & St. Vincent: Who | 2012 | Composer | Composer |
| St. Vincent: Cheerleader Music Video | 2012 | Composer | Composer |
| St. Vincent: Cruel | 2011 | Composer | Composer |
| St. Vincent: Marrow Music Video | 2009 | Composer | Composer |
| Am I OK? | 2022 | Music Department | composer: additional music (as Annie Clark) |
| The Nowhere Inn | 2020 | Music Department | musician: score vocals, guitar, synth |
| The Oscars | 2018 | Music Department | featuring: "Mystery of Love" |
| Sound of Metal | 2019 | Thanks | thanks (as Annie Clark) |
| Death of a Unicorn | 2025 | Soundtrack | performer: "DOA" |
| The Penguin | 2024 | Soundtrack | performer: "Reckless" |
| Nobody Wants This | 2024 | Soundtrack | writer: "obsessed" |
| John Mulaney Presents: Everybody's in LA | 2024 | Soundtrack | performer: "Flea" |
| The Idea of You | 2024 | Soundtrack | performer: "Digital Witness", "Actor Out of Work", "Pay Your Way in Pain" |
| The Project | 2024 | Soundtrack | writer: "Cruel Summer" (as Annie Clark) |
| Taylor Swift: The Eras Tour | 2023 | Soundtrack | writer: "Cruel Summer" (as Annie Clark) |
| Wilderness | 2023 | Soundtrack | performer: "Waiting On a Wave" |
| Yellowjackets | 2023 | Soundtrack | performer: "Sad But True" |
| Obsession | 2023 | Soundtrack | performer: "Los Ageless" |
| Late Bloomers | 2023 | Soundtrack | performer: "Fast Slow Disco" |
| The Subtle Art of Not Giving a F*ck | 2023 | Soundtrack | performer: "Pay Your Way in Pain" |
| Minions: The Rise of Gru | 2022 | Soundtrack | performer: "Funkytown" |
| WeCrashed | 2022 | Soundtrack | performer: "New York" |
| The Dropout | 2022 | Soundtrack | performer: "Pay Your Way in Pain" |
| Am I OK? | 2022 | Soundtrack | performer: "Los Ageless" |
| Saturday Night Live | 2014–2021 | Soundtrack | performer: "Pay Your Way in Pain", "The Melting of the Sun" |
| David Byrne's American Utopia | 2020 | Soundtrack | writer: "I Should Watch TV" (as Annie Clark) |
| 13 Reasons Why | 2017–2020 | Soundtrack | performer: "Fear the Future" |
| The Nowhere Inn | 2020 | Soundtrack | performer: "The Nowhere Inn" (Studio Version & Live), "New York", "Fear the Future" (Live), "Marrow" (Live), "Savior" (Studio Version & Live), "Los Ageless" (Studio Version & Live), "Hang on Me", "Pills", "Sugarboy" (Studio Version & Live), "Rattlesnake" (Live), "Fast Slow Disco" (Live), "Masseduction", "Cheerleader" (Live), "Huey Newton" (Studio Version & Live), "Happy Birthday, Johnny", "Digital Witness" (Darkside Remix & Live), "Smoking Section", "Palm Desert" |
| Aikuiset | 2019 | Soundtrack | performer: "Sugarboy" |
| Miss Bala | 2019 | Soundtrack | performer: "Los Ageless" |
| Second Act | 2018 | Soundtrack | performer: "Masseducation" |
| BoJack Horseman | 2018 | Soundtrack | performer: "Los Ageless" |
| Greta | 2018 | Soundtrack | performer: "The Strangers" |
| The Oscars | 2018 | Soundtrack | performer: "Mystery of Love" |
| The Tonight Show Starring Jimmy Fallon | 2015–2017 | Soundtrack | performer: "Slow Disco" |
| The Late Show with Stephen Colbert | 2017 | Soundtrack | performer: "New York", "Los Ageless" |
| Pete's Dragon | 2016 | Soundtrack | performer: "Something On Your Mind" |
| Gravy | 2015 | Soundtrack | performer: "The Strangers" |
| A Bigger Splash | 2015 | Soundtrack | performer: "Emotional Rescue" |
| T in the Park 2015 TV Series | 2015 | Soundtrack | performer: "Digital Witness" (as St Vincent) |
| iZombie | 2015 | Soundtrack | performer: "Prince Johnny" |
| Brows Held High | 2014 | Soundtrack | writer: "Digital Witness" (uncredited) |
| Late Show with David Letterman | 2009–2014 | Soundtrack | performer: "Bring Me Your Loves" |
| Perfect Sisters | 2014 | Soundtrack | performer: "Cruel" |
| The Twilight Saga: Breaking Dawn - Part 2 | 2012 | Soundtrack | performer: "The Antidote" |
| Thanks for Sharing | 2012 | Soundtrack | performer: "Year of the Tiger" |
| To the Wonder | 2012 | Soundtrack | performer: "Now Now" |
| Gossip Girl | 2012 | Soundtrack | performer: "Cruel", "Cheerleader" |
| Conan | 2012 | Soundtrack | performer: "Cheerleader" |
| Late Night with Jimmy Fallon | 2010 | Soundtrack | performer: "MANIAC" |
| So You Think You Can Dance | 2010 | Soundtrack | performer: "Paris is Burning" |
| The Twilight Saga: New Moon | 2009 | Soundtrack | performer: "Rosyln" |
| The Late Show with Stephen Colbert | 2017–2025 | Self | Self - Guest |
| SNL50: The Homecoming Concert | 2025 | Self | Self - Performer |
| G*ve a F*ck La: A Benefit for La Fire Relief TV Special | 2025 | Self | |
| The 67th Annual Grammy Awards | 2025 | Self | Self - Performer |
| CBeebies Bedtime Story | 2024 | Self | Self - Storyteller |
| ARTE Concert Festival TV Series | 2024 | Self | Self |
| The Graham Norton Show | 2017–2024 | Self | Self - Musical Guest |
| St. Vincent's 'All Born Screaming' Tour: Live from Brooklyn TV Special | 2024 | Self | Self |
| The Tonight Show Starring Jimmy Fallon | 2015–2024 | Self | Self - Musical Guest |
| ABC News Breakfast | 2024 | Self | Self - Musician |
| Jimmy Kimmel Live! | 2009–2024 | Self | Self - Musical Guest |
| John Mulaney Presents: Everybody's in LA | 2024 | Self | Self - Musical Guest |
| National Christmas Tree Lighting 2023 TV Special | 2023 | Self | Guest |
| 2023 Rock & Roll Hall of Fame Induction Ceremony | 2023 | Self | Self |
| Yoshiki: Under the Sky | 2023 | Self | Self |
| A Grammy Salute to the Beach Boys | 2023 | Self | Self |
| Metallica Presents: The Helping Hands Concert Live Black Carpet Pre-Show TV Special | 2022 | Self | Self |
| The 2022 Rock & Roll Hall of Fame Induction Ceremony | 2022 | Self | Self |
| Women Who Rock | 2022 | Self | Self |
| Austin City Limits | 2009–2022 | Self | Self |
| The Late Late Show with James Corden | 2022 | Self | Self - Musical Guest |
| Pirelli Calendar 2022 TV Special | 2022 | Self | Self |
| Gucci Love Parade Video | 2021 | Self | Self - Model |
| Down and Out Downtown | 2021 | Self | Self |
| Titel, Thesen, Temperamente | 2021 | Self | Self |
| What Drives Us | 2021 | Self | Self |
| Saturday Night Live | 2014–2021 | Self | Self - Musical Guest |
| MTV EMA 2020 | 2020 | Self | Self |
| Words & Music Podcast Series | 2020 | Self | Self (voice) |
| Let's Go Crazy: The Grammy Salute to Prince | 2020 | Self | Self |
| 35th Film Independent Spirit Awards | 2020 | Self | Self - Presenter |
| Jenny Lewis: Red Bull & Hennessy | 2019 | Self | Self |
| Jenny Lewis' On The Line Online | 2019 | Self | Self |
| The 61st Annual Grammy Awards | 2019 | Self | Self - Performer & Winner |
| St. Vincent: Fast Slow Disco | 2018 | Self | Self |
| The Oscars | 2018 | Self | Self - Performer (uncredited) |
| The Daily Show | 2017 | Self | Self |
| The Ellen DeGeneres Show | 2017 | Self | Self - Musical Guest |
| Power Chord TV TV Series | 2017 | Self | Self |
| St. Vincent Becomes Ambassador to Recorstorda | 2017 | Self | Self |
| Soundbreaking: Stories from the Cutting Edge of Recorded Music | 2016 | Self | Self |
| Contemporary Color | 2016 | Self | Self |
| Taylor Swift: The 1989 World Tour Live | 2015 | Self | Self - Musical Guest |
| T in the Park 2015 TV Series | 2015 | Self | Self |
| MAKERS TV Series | 2015 | Self | Self |
| The Brit Awards 2015 | 2015 | Self | Self |
| WTF with Marc Maron | 2014 | Self | Self - Guest |
| Sound Advice | 2014 | Self | Self |
| The Kate Bush Story: Running Up That Hill | 2014 | Self | Self (as Annie Clark - St. Vincent) |
| Late Show with David Letterman | 2009–2014 | Self | Self - Musical Guest |
| Later... With Jools Holland | 2014 | Self | Self |
| Over/Under | 2014 | Self | Self |
| The Colbert Report | 2012–2014 | Self | Self - Musical Guest |
| Late Night with Jimmy Fallon | 2010–2012 | Self | Self - Musical Guest |
| David Byrne & St. Vincent: Who | 2012 | Self | Self |
| Comedy Bang Bang: The Podcast | 2012 | Self | Self |
| Conan | 2012 | Self | Self - Musical Guest |
| Andrew Bird: Fever Year | 2011 | Self | Self (as Annie Clark) |
| Do You Love Me Like I Love You, Part 3: Kicking Against the Pricks Short | 2009 | Self | Self (as Annie Clark) |
| Soundtrack of Arts - Kunst in Pop und Klassik TV Mini Series | 2023 | Archive Footage | Self (archive footage) |
| Glastonbury 2022 | 2022 | Archive Footage | Self (archive footage) |