| Velma | 2023–2024 | Actress | Brenda (voice) |
| Something from Tiffany's | 2022 | Actress | Vanessa |
| Dollface | 2019–2022 | Actress | Stella Cole |
| Punk'd | 2021 | Actress | Shay |
| Miracle Workers | 2021 | Actress | Purple |
| Trese | 2021 | Actress | Alexandra Trese (English version, voice) |
| The Heiresses | 2019 | Actress | |
| The Possession of Hannah Grace | 2018 | Actress | Megan Reed |
| You | 2018 | Actress | Peach Salinger |
| Pretty Little Liars | 2010–2017 | Actress | Emily Fields |
| Logan Paul Feat. Why Don't We: Help Me Help You | 2017 | Actress | Girlfrend |
| King Bachelor's Pad | 2017 | Actress | Beauty |
| Nick Jonas: Under You | 2016 | Actress | Shay Mitchell |
| Dreamland | 2016 | Actress | Nicole |
| Mother's Day | 2016 | Actress | Tina |
| Immediately Afterlife | 2014 | Actress | Marissa |
| Glee | 2012 | Actress | Girl in Yellow Jacket (uncredited) |
| Aaron Stone | 2010 | Actress | Irina Webber |
| Rookie Blue | 2010 | Actress | Cute Girl |
| Verona | 2010 | Actress | Model (uncredited) |
| Sean Paul: Hold My Hand | 2009 | Actress | Love Interest |
| Degrassi: The Next Generation | 2009 | Actress | Model |
| Cupid's Cafe Video | 2008 | Actress | Allison |
| Thirst with Shay Mitchell | 2024 | Producer | executive producer |
| The Cleaning Lady | 2022–2024 | Producer | executive consultant |
| Almost Ready | 2019 | Producer | executive producer |
| Shay Mitchell: Chapters TV Series | 2017 | Producer | executive producer |
| The Cleaning Lady | 2024 | Additional Crew | executive consultant |
| Pretty Little Liars: We Love You to DeAth | 2014 | Thanks | special thanks |
| Pretty Little Liars: A LiArs Guide to Rosewood | 2013 | Thanks | thanks |
| Pretty Little Liars | 2011–2014 | Soundtrack | performer: "What Child Is This?" |
| The Jennifer Hudson Show | 2024 | Self | Self |
| Thirst with Shay Mitchell | 2024 | Self | Self - Host |
| The Kelly Clarkson Show | 2024 | Self | Self - Guest |
| Watch What Happens Live with Andy Cohen | 2022–2024 | Self | Self - Guest |
| Today | 2016–2024 | Self | Self - Guest |
| Entertainment Tonight | 2018–2022 | Self | Self |
| Podcrushed | 2022 | Self | Self - Guest |
| The Morning Show | 2022 | Self | Self - Actress, entrepreneur & mom (LOS ANGELES) |
| Live with Kelly and Mark | 2015–2022 | Self | Self - Guest Co-Host |
| Entertainment Tonight Canada | 2022 | Self | Self |
| Watch What Happens Live with Andy Cohen | 2022 | Self | Self - Guest |
| Trese After Dark | 2021 | Self | Self - Actress, Alexandra Trese |
| Post Malone's Celebrity World Pong League | 2020 | Self | Self - Guest |
| Architectural Digest | 2020 | Self | Self |
| Just Between Us with sisters Bailee Madison and Kaitlin Vilasuso Podcast Series | 2019 | Self | Self |
| Almost Ready | 2019 | Self | |
| iHeartRadio Music Awards 2019 | 2019 | Self | Self - Presenter |
| Let's Talk About That | 2019 | Self | Self |
| Good Mythical Morning | 2015–2019 | Self | Self |
| The IMDb Show | 2019 | Self | Self - Guest |
| Celebrity Page | 2017–2018 | Self | Self |
| The 12th Annual CNN Heroes: An All-Star Tribute TV Special | 2018 | Self | Self - Presenter |
| Made in Hollywood | 2018 | Self | Self |
| E! Live from the Red Carpet | 2018 | Self | Self |
| The E! People's Choice Awards | 2018 | Self | Self - Presenter |
| Master the Mess | 2018 | Self | Self |
| Rachael Ray | 2015–2018 | Self | Self |
| 2018 MTV Video Music Awards | 2018 | Self | Self - Presenter |
| Unqualified | 2018 | Self | Self - Guest |
| RuPaul's Drag Race All Stars | 2018 | Self | Self - Guest Judge |
| The Insider | 2014–2017 | Self | Self |
| We Day 2017 | 2017 | Self | Self - Guest |
| Inside the PLL Sheets Video | 2017 | Self | Self |
| Pretty Little Liars: A List Wrap Party | 2017 | Self | Self |
| Extra | 2017 | Self | Self |
| Teens Wanna Know | 2017 | Self | Self |
| Red Carpet Report | 2017 | Self | Self |
| 2017 MTV Movie & TV Awards | 2017 | Self | Self - Presenter |
| 9th Annual Shorty Awards Video | 2017 | Self | Self - Presenter |
| BuzzFeed Celeb | 2016–2017 | Self | Self |
| Good Morning America | 2012–2017 | Self | Self |
| Shay Mitchell: Chapters TV Series | 2017 | Self | Self |
| The Ellen DeGeneres Show | 2017 | Self | Self |
| Off the Menu TV Mini Series | 2016–2017 | Self | Self |
| Teen Choice Awards 2016 | 2016 | Self | Self - Accepting Award |
| The Tonight Show Starring Jimmy Fallon | 2016 | Self | Self |
| The Talk | 2015–2016 | Self | Self - Guest |
| MAKERS Canada TV Series | 2016 | Self | Self |
| Inside the 5 Years Video | 2016 | Self | Self |
| Homecoming: The PLL's Return Video | 2016 | Self | Self |
| A PLL Prom Video | 2016 | Self | Self |
| Celebrity Style Story | 2016 | Self | Self |
| Access Daily | 2015–2016 | Self | Self |
| A Trip to Unicorn Island | 2016 | Self | Self |
| The View | 2014–2016 | Self | Self |
| The 42nd Annual People's Choice Awards | 2016 | Self | Self - Nominee & Accepting Award |
| Young Hollywood Gives Back: A CNN Heroes Special TV Movie | 2015 | Self | Self |
| Pretty Little Liars: 5 Years Forward | 2015 | Self | Self |
| MTV Europe Music Awards 2015 | 2015 | Self | Self - Presenter |
| Talk Stoop | 2015 | Self | Self |
| Teen Choice Awards 2015 | 2015 | Self | Self - Accepting Award |
| Christmas in Rosewood: Designing the Ice Ball Video | 2015 | Self | Self |
| Shaycation | 2015 | Self | Self |
| The Meredith Vieira Show | 2015 | Self | Self - Guest |
| The Chew | 2015 | Self | Self |
| Pretty Little Liars: We Love You to DeAth | 2014 | Self | Self |
| Project Runway | 2014 | Self | Self - Guest Judge |
| Teen Choice Awards 2014 | 2014 | Self | Self - Audience Member (uncredited) |
| Pretty Little Liars: Pretty Little Scenes Video | 2014 | Self | Self |
| Pretty Little Liars: Unhooding Redcoat, Alison Is Alive | 2014 | Self | Self |
| Confessions of 'A' Lair Video | 2014 | Self | Self |
| The Writers' Room | 2014 | Self | Self |
| Bethenny | 2014 | Self | Self |
| Katie | 2014 | Self | Self |
| Hey Tucker! | 2013 | Self | Shay |
| The 7th Annual CNN Heroes: An All-Star Tribute TV Special | 2013 | Self | Self - Presenter |
| TeenNick Halo Awards TV Special | 2013 | Self | Self |
| Pretty Little Liars Live TV Special | 2013 | Self | Self |
| Teen Choice Awards 2013 | 2013 | Self | Self - Accepting Award |
| Hello! Hollywood | 2013 | Self | Self |
| Pretty Little Liars: And the 'A' Network Video | 2013 | Self | Self |
| Nikki & Sara Live | 2013 | Self | Self |
| Teen Choice Awards 2012 | 2012 | Self | Self - Presenter |
| The Revolution | 2012 | Self | Self |
| Pretty Little Liars: Men of Mystery Video | 2012 | Self | Self |
| Punk'd | 2012 | Self | Self (as Shannon 'Shay' Mitchell) |
| Just Yell Fire: Campus Life | 2012 | Self | Self |
| The Mo'Nique Show | 2011 | Self | Self |
| 2011 MuchMusic Awards | 2011 | Self | Self |
| 13th Annual Young Hollywood Awards | 2011 | Self | Self |
| MTV New Year's Bash 2011 | 2010 | Self | Self |
| Teen Choice Awards 2010 | 2010 | Self | Self - Presenter |
| Made in Hollywood: Teen Edition | 2010 | Self | Self |
| You | 2019–2021 | Archive Footage | Peach Salinger (archive footage) |
| Entertainment Tonight | 2019 | Archive Footage | Self (archive footage) |
| Celebrity Page | 2018–2019 | Archive Footage | Self (archive footage) |
| Extra | 2015–2017 | Archive Footage | Self |
| The Insider | 2016 | Archive Footage | Self (archive footage) |
| Live with Kelly and Mark | 2015 | Archive Footage | Self (archive footage) |