| Tegan and Sara: I Can't Grow Up Music Video | 2022 | Actress | |
| Tegan and Sara: I Know I'm Not the Only One Music Video | 2020 | Actress | Tegan and Sara |
| Tegan and Sara: Dying to Know Music Video | 2016 | Actress | Tegan and Sara |
| Tegan and Sara: Faint of Heart Music Video | 2016 | Actress | Tegan and Sara |
| Tegan and Sara: BWU | 2016 | Actress | Tegan and Sara |
| Tegan and Sara: U-Turn Music Video | 2016 | Actress | Tegan and Sara |
| Night Terrors of 1927: When You Were Mine Music Video | 2014 | Actress | Tegan and Sara |
| Tegan and Sara: Goodbye, Goodbye Music Video | 2013 | Actress | Tegan and Sara |
| Tegan and Sara: I Was a Fool Music Video | 2013 | Actress | Tegan and Sara |
| Tegan and Sara: Closer | 2012 | Actress | Tegan and Sara |
| Three's a Crowd: a Who Could've Done This? Prequel. Short | 2023 | Composer | Composer |
| Two Could've Done This.. Short | 2023 | Composer | Composer |
| Tegan and Sara: I Know I'm Not the Only One Music Video | 2020 | Composer | Composer |
| Boats N Bikes TV Series | 2017 | Composer | Composer |
| The Silver Lake Chorus: Hold Up For Music Video | 2015 | Composer | Composer |
| Get Along | 2011 | Composer | Composer |
| The Oscars | 2015 | Music Department | featuring (as Tegan & Sara) |
| Night Terrors of 1927: When You Were Mine Music Video | 2014 | Music Department | vocals |
| One Tree Hill | 2011 | Music Department | song performed by |
| It Remains Unsaid | 2011 | Thanks | special thanks |
| Altitude | 2010 | Thanks | special thanks |
| The Nevermind Year TV Movie | 2004 | Thanks | thanks |
| The Masked Singer | 2024 | Soundtrack | performer: "Closer" |
| My Lady Jane | 2024 | Soundtrack | performer: "Rebel Rebel" |
| Scott Pilgrim Takes Off | 2023 | Soundtrack | performer: "You Wouldn't Like Me" |
| DarkUnicorn2003 (Majed Ahmed) Trip TV Series | 2023 | Soundtrack | performer: "Everything Is AWESOME!!! (feat. The Lonely Island)" |
| You Are So Not Invited to My Bat Mitzvah | 2023 | Soundtrack | performer: "Cloud 9" |
| The Marvelous Mrs. Maisel | 2023 | Soundtrack | performer: "Girls Talk" |
| Crush | 2022 | Soundtrack | performer: "Faded Like a Feeling" |
| America's Morning Headquarters | 2022 | Soundtrack | performer: "Everything Is AWESOME!!!" (as "Everything is Awesome!!!") |
| Happiest Season | 2020 | Soundtrack | performer: "Make You Mine This Season" |
| The New Mutants | 2020 | Soundtrack | performer: "Closer" |
| The Package | 2018 | Soundtrack | performer: "Bad Ones" |
| Back to the Land with Kate Humble TV Series | 2018 | Soundtrack | performer: "I'm Not Your Hero" (uncredited) |
| Nightmare Pets: SOS TV Mini Series | 2018 | Soundtrack | performer: "Drove Me Wild", "Stop Desire" (uncredited) |
| To All the Boys I've Loved Before | 2018 | Soundtrack | performer: "Bad Ones" |
| Lean on Pete | 2017 | Soundtrack | performer: "Stop Desire" |
| Friends from College | 2017 | Soundtrack | performer: "Closer" |
| Riverdale | 2017 | Soundtrack | performer: "Boyfriend" (uncredited) |
| Grey's Anatomy | 2005–2016 | Soundtrack | performer: "You Wouldn't Like Me" |
| The Tonight Show Starring Jimmy Fallon | 2016 | Soundtrack | performer: "Boyfriend" |
| SMG4 | 2016 | Soundtrack | performer: "Everything is Awesome (Awesome Remixxx!!!)" |
| The Intervention | 2016 | Soundtrack | performer: "Fade Out" |
| The Intern | 2015 | Soundtrack | performer: "Closer" |
| Lip Sync Battle | 2015 | Soundtrack | performer: "Everything Is Awesome" |
| American Dad! | 2015 | Soundtrack | performer: "I Can't Take It" (uncredited) |
| The Oscars | 2015 | Soundtrack | performer: "Everything Is Awesome" |
| The DUFF | 2015 | Soundtrack | performer: "How Come You Don't Want Me" (as Tegan & Sara) |
| Pretty Little Liars | 2015 | Soundtrack | performer: "Burn Your Life Down" (uncredited) |
| Night Terrors of 1927: When You Were Mine Music Video | 2014 | Soundtrack | performer: "When You Were Mine" |
| BoJack Horseman | 2014 | Soundtrack | performer: "Closer" (uncredited) |
| Young & Hungry | 2014 | Soundtrack | performer: "Closer" (uncredited) |
| Guapas | 2014 | Soundtrack | performer: "Alligator" |
| Endless Love | 2014 | Soundtrack | performer: "Don't Find Another Love" |
| The Lego Movie | 2014 | Soundtrack | performer: "Everything is Awesome (Awesome Remixxx!!!)" |
| Féminin/Féminin | 2014 | Soundtrack | Soundtrack ("Closer (The Knocks Remix)") |
| Dallas Buyers Club | 2013 | Soundtrack | Soundtrack ("Shudder to Think", uncredited) |
| Sunday Brunch | 2013 | Soundtrack | performer: "I Was a Fool" |
| Awkward. | 2013 | Soundtrack | performer: "Drove Me Wild" |
| G.B.F. | 2013 | Soundtrack | performer: "Body Work", "Closer" |
| The Tonight Show with Jay Leno | 2013 | Soundtrack | performer: "Closer" (uncredited) |
| Girls | 2013 | Soundtrack | performer: "Fool To Cry" (uncredited) |
| David Guetta & Alesso Feat. Tegan and Sara: Every Chance We Get We Run Music Video | 2012 | Soundtrack | Soundtrack ("Every Chance We Get We Run") |
| Degrassi: The Next Generation | 2012 | Soundtrack | performer: "Closer " (uncredited) |
| 90210 | 2009–2012 | Soundtrack | performer: "Call It Off" (uncredited) |
| Late Show with David Letterman | 2008–2012 | Soundtrack | performer: "Closer" |
| Nashville | 2012 | Soundtrack | performer: "Body Work" (uncredited) |
| Conan | 2012 | Soundtrack | performer: "Closer" |
| One Tree Hill | 2003–2011 | Soundtrack | performer: "I Don't Want to Be" |
| Being Erica | 2009–2010 | Soundtrack | performer: "Where Does the Good Go" |
| Rock Band 3 | 2010 | Soundtrack | performer: "The Con" |
| Altitude | 2010 | Soundtrack | performer: "Divided" |
| Rookie Blue | 2010 | Soundtrack | performer: "Hell" |
| The Vampire Diaries | 2009–2010 | Soundtrack | performer: "The Ocean" |
| Melrose Place | 2010 | Soundtrack | Soundtrack ("Feel It In My Bones", uncredited) |
| The Tonight Show with Conan O'Brien | 2009 | Soundtrack | performer: "Hell" (uncredited) |
| The Last New Year | 2009 | Soundtrack | performer: "The Con", "You Are Ten Years Ago" |
| Ghost Whisperer | 2007 | Soundtrack | performer: "Burn Your Life Down" (uncredited) |
| Late Night with Conan O'Brien | 2007 | Soundtrack | performer: "Back in Your Head" |
| Veronica Mars | 2005–2006 | Soundtrack | writer: "I Know I Know I Know" |
| Subterranean TV Series | 2005 | Soundtrack | performer: "Speak Slow" |
| The 24th Day | 2004 | Soundtrack | performer: "Don't Confess" |
| The Great Upstanding Member Short | 2003 | Soundtrack | Soundtrack ("City Girl") |
| What's New, Scooby-Doo? | 2003 | Soundtrack | performer: "Time Running" |
| 120 Minutes | 2003 | Soundtrack | performer: "I Hear Noises" |
| Sweet November | 2001 | Soundtrack | performer: "My Number" |
| Just Like Heaven TV Special | 2024 | Self | Self |
| The 2024 Juno Awards | 2024 | Self | Themselves |
| CBS Mornings | 2023 | Self | Themselves |
| The Late Late Show with James Corden | 2016–2022 | Self | Themselves - Musical Guests |
| The Tonight Show Starring Jimmy Fallon | 2016–2022 | Self | Themselves - Musical Guests |
| Late Night with Seth Meyers | 2022 | Self | Themselves - Musical Guests |
| Women Who Rock | 2022 | Self | Self |
| Vincint: Getaway Feat. Tegan and Sara TV Special | 2021 | Self | |
| Today | 2020–2021 | Self | Themselves - Musical Guests |
| The Kelly Clarkson Show | 2020 | Self | Themselves - Musical Guests |
| Pop Life TV Mini Series | 2019 | Self | Themselves - Guest |
| A Little Late with Lilly Singh | 2019 | Self | Themselves |
| The Late Show with Stephen Colbert | 2016–2019 | Self | Themselves |
| iHeartRadio Canada Commercial Video | 2017 | Self | Themselves |
| Larry King Now | 2016 | Self | Themselves - Guest |
| Good Morning America | 2016 | Self | Themselves - Musical Guests |
| FIFA Women's World Cup Canada 2015: Opening Ceremony TV Special | 2015 | Self | |
| The Oscars | 2015 | Self | Themselves - Performer |
| Conan | 2012–2014 | Self | Themselves - Musical Guest |
| Sound Advice | 2014 | Self | Themselves |
| Above Average Presents | 2014 | Self | Themselves |
| 43rd Annual JUNO Awards 2014 TV Special | 2014 | Self | Themselves - Performer |
| iHeartRadio Jingle Ball 2013 | 2013 | Self | Themselves - Performers |
| Sunday Brunch | 2013 | Self | Themselves - Guests (as Tegan & Sara) |
| 2013 New Now Next Awards TV Special | 2013 | Self | Themselves |
| The Tonight Show with Jay Leno | 2008–2013 | Self | Themselves - Musical Guest |
| Big Morning Buzz Live | 2013 | Self | Themselves - Musical Guest |
| Jimmy Kimmel Live! | 2013 | Self | Self - Musical guest |
| Late Show with David Letterman | 2001–2012 | Self | Themselves - Musical Guest |
| The Gorburger Show | 2012 | Self | Themselves |
| Get Along | 2011 | Self | Themselves |
| The Hour | 2010 | Self | Self |
| The Tonight Show with Conan O'Brien | 2009 | Self | Themselves - Musical Guest |
| Human Giant | 2007 | Self | Themselves |
| Entertainment Tonight Canada | 2005–2023 | Self | Self |
| Live 8 | 2005 | Self | Themselves |
| Late Night with Conan O'Brien | 2005 | Self | Themselves - Musical Guest |
| The Late Late Show with Craig Kilborn | 2004 | Self | Themselves |
| The 11th Annual YTV Achievement Awards TV Special | 2000 | Self | Themselves - winners & performers |